Ontology highlight
ABSTRACT:
INSTRUMENT(S): TripleTOF 5600
ORGANISM(S): Homo Sapiens (human)
SUBMITTER: Xiao Yang
LAB HEAD: Lei Chu
PROVIDER: PXD040593 | Pride | 2023-05-10
REPOSITORIES: Pride
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Yang Xiao X Lu Yang Y Zhou Hang H Jiang Hai-Tao HT Chu Lei L
Frontiers in cell and developmental biology 20230316
Low back pain (LBP) is a prevalent health problem worldwide that affects over 80% of adults during their lifetime. Intervertebral disc degeneration (IDD) is a well-recognized leading cause of LBP. IDD is classified into five grades according to the Pfirrmann classification system. The purpose of this study was to identify potential biomarkers in different IDD grades through an integrated analysis of proteome sequencing (PRO-seq), bulk RNA sequencing (bRNA-seq) and single-cell RNA sequencing (scR ...[more]