Proteomics

Dataset Information

0

LExtracellular vesicle proteins of E. coli O83


ABSTRACT: EcO83-Outer membrane vesicles (OMVs) were isolated by ultracentrifugation and characterised with respect to their number, morphology, composition of lipopolysaccharide and proteins, as well as immunomodulatory potential.

INSTRUMENT(S): Q Exactive HF

ORGANISM(S): Escherichia Coli

TISSUE(S): Cell Suspension Culture

SUBMITTER: Johan Palmfeldt  

LAB HEAD: Johan Palmfeldt

PROVIDER: PXD040963 | Pride | 2024-05-24

REPOSITORIES: Pride

Dataset's files

Source:
Action DRS
401-Brad-1-OMV-A.raw Raw
403-Brad-4-con-OMV-A.raw Raw
405-Brad-Coli-A.raw Raw
407-Brad-2-OMV-B.raw Raw
409-Brad-5-con-OMV-B.raw Raw
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Publications


<h4>Background</h4>E. coli O83 (Colinfant Newborn) is a Gram-negative (G-) probiotic bacterium used in the clinic. When administered orally, it reduces allergic sensitisation but not allergic asthma. Intranasal administration offers a non-invasive and convenient delivery method. This route bypasses the gastrointestinal tract and provides direct access to the airways, which are the target of asthma prevention. G- bacteria such as E. coli O83 release outer membrane vesicles (OMVs) to communicate w  ...[more]

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