Proteomics

Dataset Information

0

Proteins that interact with CLK2 (WT) or CLK2 (T343A)


ABSTRACT: Our results show that CLK2 undergoes liquid-liquid phase separation (LLPS) in response to heat shock stress. Phosphorylation of CLK2 at T343 prevents the LLPS of CLK2. To identify the proteins that recruited to the CLK2 condensates, we immunoprecipitated CLK2 (WT) or (T343A) proteins with FLAG antibody and performed mass spectrometry to detect the interacting proteins.

INSTRUMENT(S): Orbitrap Exploris 480

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Permanent Cell Line Cell, Cell Culture

DISEASE(S): Glioblastoma

SUBMITTER: Wei Wang  

LAB HEAD: Wei Wang

PROVIDER: PXD040997 | Pride | 2023-11-06

REPOSITORIES: Pride

Dataset's files

Source:
Action DRS
22072006_WB_343.raw Raw
22072006_WB_CLK2.raw Raw
22072006_WB_GFP.raw Raw
Control_WT_peptide.summary.xlsx Xlsx
Control_WT_protein.summary.xlsx Xlsx
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