Ontology highlight
ABSTRACT:
INSTRUMENT(S): TripleTOF 5600
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Urinary Bladder
DISEASE(S): Bladder Transitional Cell Carcinoma
SUBMITTER: Franz Dressler
LAB HEAD: Franz Friedrich Dressler
PROVIDER: PXD041873 | Pride | 2024-06-16
REPOSITORIES: Pride
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1_2.wiff.scan | Wiff |
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Nature communications 20240527 1
Urothelial bladder cancer (UC) has a wide tumor biological spectrum with challenging prognostic stratification and relevant therapy-associated morbidity. Most molecular classifications relate only indirectly to the therapeutically relevant protein level. We improve the pre-analytics of clinical samples for proteome analyses and characterize a cohort of 434 samples with 242 tumors and 192 paired normal mucosae covering the full range of UC. We evaluate sample-wise tumor specificity and rank bioma ...[more]