Proteomics

Dataset Information

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Secretome analysis of Pancreatic Cancer Spheroid with myeloid cell infiltration


ABSTRACT: Pancreatic ductal adenocarcinoma (PDAC) is one of the most hypoxic, lethal, and treatment resistant cancers. Due to its desmoplastic and hypoxic nature along with the abundance of myeloid cell infiltration and scare T cell infiltration, PDAC is considered a cold tumor. Using MiaPaCA-2 as a PDAC spheroid model with hypoxic core grown in serum-free defined media and immune cell infiltration, we assessed the modulation of PDAC secretome and characterized immunomodulatory factors secreted.

INSTRUMENT(S): Q Exactive HF

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Cell Culture, Epithelial Cell Of Pancreas

DISEASE(S): Pancreatic Cancer,Pancreatic Ductal Adenocarcinoma

SUBMITTER: Apple Tay  

LAB HEAD: Andreas Lundqvist

PROVIDER: PXD044177 | Pride | 2023-12-15

REPOSITORIES: Pride

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