Proteomics

Dataset Information

0

Exploration of Mycobacterium tuberculosis CYP138 Function by Quantitative proteome


ABSTRACT: With the widespread of drug-resistant Mycobacterium tuberculosis (Mtb), anti-TB drugs with novel structures and targets are urgently needed to prevent the prevalence of drug-resistant strains. For the past few decades, many Mtb CYPs been structurally and functionally characterized, and some of them were proved to be potential drug targets. CYP138 belongs to the Mtb CYPs whose structures and functions are still unclear. In our study, to discover differentially expressed proteins, a cyp138-knockout strain was built, and the function of CYP138 was speculated by the comparison between cyp138-knockout and wild-type strains through 6-plex TMT-labeling-based quantitative proteomic approach.

INSTRUMENT(S): Orbitrap Fusion Lumos

ORGANISM(S): Mycobacterium Tuberculosis H37rv

SUBMITTER: Yun Lu  

LAB HEAD: Xuefu You

PROVIDER: PXD045505 | Pride | 2024-03-10

REPOSITORIES: pride

Dataset's files

Source:
Action DRS
checksum.txt Txt
mtbf1.raw Raw
mtbf2.raw Raw
mtbf3.raw Raw
mtbf4.raw Raw
Items per page:
1 - 5 of 9

Similar Datasets

2023-03-09 | PXD035802 | Pride
2022-05-20 | PXD030883 | Pride
2023-11-17 | E-MTAB-13058 | biostudies-arrayexpress
2018-06-25 | PXD009549 | Pride
2022-02-16 | PXD030239 | Pride
2015-03-10 | E-PROT-1 | biostudies-arrayexpress
2018-08-02 | GSE118008 | GEO
2018-08-02 | GSE118021 | GEO
2018-08-02 | GSE118018 | GEO
2018-08-07 | GSE118196 | GEO