Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive HF
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Subcutaneous Preadipocyte
DISEASE(S): Simpson-golabi-behmel Syndrome Type 1
SUBMITTER: Alix Sarah Aldehoff
LAB HEAD: Kristin Schubert
PROVIDER: PXD045767 | Pride | 2024-06-13
REPOSITORIES: Pride
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iScience 20240410 6
Obesity, characterized by enlarged and dysfunctional adipose tissue, is among today's most pressing global public health challenges with continuously increasing prevalence. Despite the importance of post-translational protein modifications (PTMs) in cellular signaling, knowledge of their impact on adipogenesis remains limited. Here, we studied the temporal dynamics of transcriptome, proteome, central carbon metabolites, and the acetyl- and phosphoproteome during adipogenesis using LC-MS/MS combi ...[more]