Proteome analysis of HepG2 WT and mitochondrial apolipoprotein MIC26 knockout cells under normo- and hyperglycemic conditions
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ABSTRACT: Increased amounts of the mitochondrial apolipoprotein O /MIC26 were found in diabetic patients along with lipid accumulation in murine liver upon MIC26 expression. MIC26 is a MICOS complex constituent present in the mitochondrial inner membrane. Here, we employed a proteomics analysis approach in WT and MIC26 knockout HepG2 cellular models in normoglycemic and hyperglycemic conditions.
INSTRUMENT(S): Orbitrap Fusion Lumos
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Hepatocyte, Liver
SUBMITTER: Anja Stefanski
LAB HEAD: Kai Stühler
PROVIDER: PXD047246 | Pride | 2024-09-13
REPOSITORIES: Pride
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