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Human conjunctival fibroblasts-LC-MS/MS

ABSTRACT: The underlying mechanisms of conjunctival fibrosis are complex and involve multiple factors and signaling pathway. Wnt/β-catenin signaling pathway plays an important role in organelle fibrosis. In this study, ICG-001 that inhibiting Wnt/β-catenin pathway has been applied in TGFβ1-induced fibrosis model of primary human conjunctival fibroblasts (HConFs). To verify the regulator of TGFβ1-induced conjunctival fibrosis, 4D DIA technology and proteomics analysis were used to identify the differentially expressed genes and the enrichment KEGG pathways.

INSTRUMENT(S): timsTOF Pro

ORGANISM(S): Homo Sapiens (human)

SUBMITTER: Biting Zhou

LAB HEAD: Biting Zhou

PROVIDER: PXD051023 | Pride | 2024-05-13

REPOSITORIES: Pride

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			Action	DRS
	Search.rar	Other
	XA04020DA_CON1_Slot1-28_1_19847.d.rar	Other
	XA04020DA_CON2_Slot1-29_1_19848.d.rar	Other
	XA04020DA_CON3_Slot1-30_1_19849.d.rar	Other
	XA04020DA_ICG1_Slot1-34_1_19855.d.rar	Other

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