Dataset Information
Tissue proteome of visceral, subcutaneous and brown adipose as well as liver tissues in an obese mouse model after dietary exposure to the emerging phthalate substitute DINCH
Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive HF
ORGANISM(S): Mus Musculus (mouse)
TISSUE(S): Brown Adipose Tissue, Liver, White Adipose Tissue, Adipose Tissue, Abdominal Adipose Tissue, Subcutaneous Adipose Tissue
DISEASE(S): Obesity,Overweight
SUBMITTER: 
Alix Sarah Aldehoff
LAB HEAD: Kristin Schubert
PROVIDER: PXD054970 | Pride | 2025-02-03
REPOSITORIES: Pride
Dataset's files
| Action | DRS | |||
|---|---|---|---|---|
| 147_BAT_female_mix10_F1.raw | Raw | |||
| 147_BAT_female_mix10_F2.raw | Raw | |||
| 147_BAT_female_mix11_F1.raw | Raw | |||
| 147_BAT_female_mix11_F2.raw | Raw | |||
| 147_BAT_female_mix12_F1.raw | Raw |
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Publications
Metabolic and molecular Characterization, following dietary exposure to DINCH, Reveals new Implications for its role as a Metabolism-Disrupting chemical.
Environment international 20250126
Plastic materials are ubiquitous, leading to constant human exposure to plastic additives such as plasticizers. There is growing evidence that plasticizers may contribute to obesity due to their disruptive effects on metabolism. Alternatives like diisononylcyclohexane-1,2-dicarboxylate (DINCH) are replacing traditional phthalates such as di-(2-ethylhexyl) phthalate (DEHP), which are now banned due to their proven harmful health effects. While DINCH is considered a safer alternative to DEHP and n ...[more]
