Phosphoproteomic analysis of hypothalamic GT1-7 neurons
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ABSTRACT: To elucidate the mechanism of neuronal activation, we conducted a global quantitative phosphoproteomic analysis of hypothalamic neurons treated with Raptin or PBS. By COG analysis of the differentially expressed phosphorylation protein, we found obvious alterations of transport and catabolism, as well as cell motility. By conducting a KEGG analysis using phosphoproteomic data, we identified the PI3K-AKT pathway.
INSTRUMENT(S): timsTOF Pro
ORGANISM(S): Mus Musculus (mouse)
TISSUE(S): Cell Culture
SUBMITTER:
Hui Peng
LAB HEAD: Xianghang Luo
PROVIDER: PXD059980 | Pride | 2025-01-27
REPOSITORIES: pride
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