Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

TCC in pluripotent and differentiated cells

ABSTRACT: TCC in pluripotent and differentiated cells

PROVIDER: PRJEB14689 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	ERR1514480_1.fastq.gz	Fastqsanger.gz
	ERR1514480_2.fastq.gz	Fastqsanger.gz
	ERR1514490_1.fastq.gz	Fastqsanger.gz
	ERR1514490_2.fastq.gz	Fastqsanger.gz
	ERR1514500_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 76

Similar Datasets

TCC in pluripotent and differentiated cells

Project description:Regulation of gene expression underlies the establishment and maintenance of cell identity. Chromatin structure and gene activity are linked. Recently CTCF anchored loops have been described as major features of chromatin organisation. However, the dynamics and role for these structures in differentiation is unknown. We used Tethered Chromatin Conformation Capture (TCC) to assess for the dynamics of CTCF-anchor loop formation upon differentiation of mouse embryonic stem cells (ESC) and neural stem cells (NSC).

2018-11-08 | E-MTAB-4870 | biostudies-arrayexpress

Gene expression of differentiated human induced pluripotent stem cells

Project description:Gene expression of differentiated human induced pluripotent stem cells

| PRJNA777961 | ENA

Engraftable multilineage hematopoietic cells differentiated from induced human pluripotent stem cells

Project description:Engraftable multilineage hematopoietic cells differentiated from induced human pluripotent stem cells

| PRJNA973621 | ENA

HiC/TCC

Project description:HiC/TCC data of barley (H. vulgare) plants

| PRJEB14169 | ENA

Hyperosmolarity stress associated proteomic changes in induced pluripotent stem cells.

Project description:Comparison of hyperosmolarity stress associated proteomic changes between induced pluripotent stem cells (hiPSCs/IMR90-01) and differentiated SH-SY5Y cells.

2020-10-23 | MSV000086363 | MassIVE

Recurrent Variations in DNA Methylation in Human Pluripotent Stem Cells and their Differentiated Derivatives

Project description:This SuperSeries is composed of the following subset Series: GSE30652: Recurrent Variations in DNA Methylation in Human Pluripotent Stem Cells and their Differentiated Derivatives [Illumina HT12v3 Gene Expression] GSE30653: Recurrent Variations in DNA Methylation in Human Pluripotent Stem Cells and their Differentiated Derivatives [Illumina Infinium 27K DNA Methylation] GSE31848: Recurrent Variations in DNA Methylation in Human Pluripotent Stem Cells and their Differentiated Derivatives [Illumina Infinium 450K DNA Methylation] Refer to individual Series

2012-05-13 | E-GEOD-30654 | biostudies-arrayexpress

RNA-Seq of GNRH1 neurons differentiated from human pluripotent stem cells

Project description:RNA-Seq of GNRH1 neurons differentiated from human pluripotent stem cells

| PRJEB32451 | ENA

Expression data from human pluripotent stem cells and differentiated cells treated with pluripotent-specific inhibitors

Project description:The use of human pluripotent stem cells (hPSCs) in cell therapy is hindered by the tumorigenic risk from residual undifferentiated cells. Here we performed a high-throughput screen of over 52,000 small molecules, and identified 15 highly selective cytotoxic inhibitors of hPSCs (PluriSIns). Cellular and molecular analyses revealed that the most selective compound, PluriSIn #1, is a pluripotent-specific inhibitor of stearoyl-coA desaturase (SCD1), the key enzyme in the biosynthesis of monounsaturated fatty acids (MUFA). SCD1 inhibition in hPSCs induced ER stress, protein synthesis attenuation, and apoptosis of these cells, revealing that MUFA biosynthesis is crucial for their survival. PluriSIn #1 was also cytotoxic toward the ICM cells of mouse embryos, indicating that the dependence on SCD1 is inherent to the pluripotent state. Finally, application of PluriSIn #1 prevented teratoma formation from tumorigenic undifferentiated cells. Our novel method to eliminate undifferentiated cells from culture should thus increase the safety of hPSC-based treatments. Expression data from undifferentiated and differentiated human embryonic stem cells. Total RNA was isolated from undifferentiated human pluripotent stem cells grown on matrigel with mTeSR1 medium, or from early endodermal progenitor cells differentiated from human embryonic stem cells.

2013-01-22 | E-GEOD-37040 | biostudies-arrayexpress

Induction of meiosis by embryonic gonadal somatic cells differentiated from pluripotent stem cells

Project description:Induction of meiosis by embryonic gonadal somatic cells differentiated from pluripotent stem cells

| PRJNA752274 | ENA

RNA-Seq of FGF8 treated neural progenitor cells differentiated from human pluripotent stem cells

Project description:RNA-Seq of FGF8 treated neural progenitor cells differentiated from human pluripotent stem cells

| PRJEB53136 | ENA