Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

ABSTRACT: A 31-bp indel in the 5UTR of the chicken GNB1L gene.

PROVIDER: PRJEB36864 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	indel_in_GNB1L.vcf.gz	Vcf
	indel_in_GNB1L.vcf.gz.tbi	Vcf

Items per page:

1 - 2 of 2

Similar Datasets

A 31-bp indel in the 5UTR of the chicken GNB1L gene.

Project description:Tuanhui_et_al_2020: A 31-bp indel in the 5UTR of the chicken GNB1L gene.

2021-10-19 | PRJEB36864 | EVA

Project description:A 51-bp indel in the first intron of the chicken PTH1R gene.

| PRJEB36115 | ENA

Project description:A 173-bp indel in the promoter region of the chicken GSTA2 gene.

| PRJEB74769 | ENA

Project description:A 65-bp indel in the fifth intron of the chicken GOLGB1gene.

| PRJEB37183 | ENA

rs143348853 in vitro DNA pulldown

Project description:Non-coding variants coordinate transcription factor (TF) binding and chromatin mark enrichment changes over regions spanning >100 kb. We named these molecularly coordinated regions “variable chromatin modules” (VCMs), providing a conceptual framework of how regulatory variation might shape complex traits. To better understand the molecular mechanisms underlying VCM formation, here, we mechanistically dissect an uncharacterized VCM-modulating non-coding variant that is associated with reduced chronic lymphocytic leukemia (CLL) predisposition and disease progression. This common, germline variant constitutes a 5-bp indel that controls the activity of an AXIN2 gene-linked VCM by creating a MEF2 binding site, which, upon binding, activates a super-enhancer-like regulatory element. This triggers a big change in TF binding activity and chromatin state at an enhancer cluster spanning >150 kb, coinciding with long-range chromatin compaction and AXIN2 up-regulation. Our results support a model in which the indel acts as an AXIN2 VCM-activating TF nucleation event, which modulates CLL pathology.

2022-04-21 | PXD029313 | Pride

A 51-bp indel in the first intron of the chicken PTH1R gene.

Project description:Tuanhui_et_al_2019: A 51-bp indel in the first intron of the chicken PTH1R gene.

2020-01-27 | PRJEB36115 | EVA

A 173-bp indel in the promoter region of the chicken GSTA2 gene.

Project description:Tuanhui_et_al_2024: A 173-bp indel in the promoter region of the chicken GSTA2 gene.

2024-04-15 | PRJEB74769 | EVA

Project description:A novel 43-bp indel polymorphism in intron 1 from the HS6ST3 gene

| PRJEB26477 | ENA

Indel array-based genotyping of pupariation site preference among Drosophila sechellia backcross progeny

Project description:We identified 6,975 insertion/deletion events of between 10 and 100 bp in length from the Drosophila simulans and Drosophila sechellia Mercator/MAVID genomic sequence alignment. Replicate pure samples of Drosophila simulans and Drosophila sechellia gDNA were competitively hybridized to measure the expected relative hybridization intensity of alleles from each species. We used these measured intensities to assess the likelihood that the hybridization signal at each probe in an experimental animal reflected homozygosity or heterozygosity at that locus. Indel array Agilent-022089 sim-sech.v.1.3

2013-02-26 | E-GEOD-44443 | biostudies-arrayexpress

Project description:Two 23-bp indels in the promoter of the chicken NUDT15 gene.

| PRJEB47912 | ENA