Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

ScRNA-seq of organoids derived from young and old mice livers

ABSTRACT: scRNA-seq of organoids derived from young and old mice livers

PROVIDER: PRJEB48427 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other
	ERR7184235_1.fastq.gz	Fastqsanger.gz
	ERR7184235_2.fastq.gz	Fastqsanger.gz

Items per page:

1 - 3 of 3

Similar Datasets

scRNA-seq of organoids derived from young and old mice livers

Project description:We set up liver-derived organoids to study the ageing progenitor population. We detected epigenetic and transcriptional memory in organoids derived from old mice accompanied by alterations in drug and fatty acid metabolism pathways, similar to phenotypes observed in the liver itself.

2024-11-30 | E-MTAB-11097 | biostudies-arrayexpress

Bulk RNA-seq of organoids derived from young and old mice livers

Project description:Bulk RNA-seq of organoids derived from young and old mice livers

| PRJEB48152 | ENA

scRNA-seq of mouse liver tissue derived from young and old mice

Project description:We want to investigate how cells in the specific zones in murine liver are affected by age-related changes of the microenvironment. To this end, we generated high-quality scRNA-seq dataset of hepatocytes using Smart-seq3express from 2 young (3-5 months) and 2 old (18-20 months) male mice. Livers were perfused and viable hepatocytes were FACS-sorted based on size. In addition, we recorded ploidy levels of hepatocytes. We retained 545 hepatocytes in total after initial filtering.

2023-11-01 | E-MTAB-12579 | biostudies-arrayexpress

Bulk RNA-seq of organoids derived from young and old mice livers

2024-11-30 | E-MTAB-11060 | biostudies-arrayexpress

scRNA-seq data from GLI3 KO in brain organoids

Project description:To study the effect of GLI3 knockout in brain organoids, we collected scRNA-seq data from 45 day old brain organoids with GLI3 KO

2022-08-19 | E-MTAB-11997 | biostudies-arrayexpress

Single cell RNA-seq of brain from young and old mice

Project description:We report the scRNA-seq of cells isolated from brain of young and old mice.

2022-08-25 | GSE178957 | GEO

Bulk RNA-seq of young and aged livers following influenza A virus infection

Project description:Aging is known to alter the host repsonse to influenza infection. Here, we use bulk RNA sequencing (bulk RNA-seq) to identify cellular changes in the livers of young (16-week-old) and aged (80-week-old) mice following influenza infection.

2023-09-05 | GSE202323 | GEO

Single cell RNA-seq of skeletal muscle from young and old mice

Project description:We report the scRNA-seq of mononuclear cells isolated from skeletal muscle of young and old mice.

2022-05-20 | GSE172410 | GEO

RNA-seq reveals differences in liver gene expression rhythms between young and old mice

Project description:Purpose: We used RNA-seq to compare daily rhythms of gene expression in livers of young and old mice. Methods: Livers of young and old mice were processed for RNA-seq at 4-h interval across 2 days. Gene expression level was analyzed by hisat2 and StringTie. Results: We obtained ~10 million high quality sequencing reads per time point per sample after quality control and alignment. Gene expression levels of ~19,000 transcripts were obtained for both age groups. We found genome-wide differenes in gene expression level as well as rhythms in gene expression. Conclusions: Our study revealed genomwide differences in the level and rhythm of liver gene expression between young and old mice.

2019-12-31 | GSE113745 | GEO

scRNA-seq of mouse liver tissue derived from young and old mice

Project description:scRNA-seq of mouse liver tissue derived from young and old mice

| PRJEB59597 | ENA