Project description:Goats are adapted efficiently in different agro-climatic conditions. Goat milk has several unexplored health-promoting properties that need to be investigated scientifically and promoted commercially. Goat milk is mainly consumed in family and plays a pivotal role in fulfilling the nutritional requirement of older people, pregnant women and children. There has been considerable interest in goat milk protein due to availability of different bioactive peptides, which have nutraceutical applications. Secondly, goat milk is being used for treatment of different disease, allergy and heat stress condition. Therefore, the milk proteome analysis appears to be timely and required for future industrial application with respect to human health and nutrition. 2-DGE analysis of identified protein variants was performed and further identification of proteins was carried out through LC-MS/MS. variant samples from 15 breeds were resolved by 2DGE and spots were identified and analysed by LC-MS/MS from 15 different breeds for presence of unique peptides.
Project description:OMIA Capra_hircus ARS1 variants 7_10_2021: goat variants listed in OMIA - the Online Mendelian Inheritance in Animals database, https://omia.org/
PubMed IDs are listed for individual variants in the VCF
Project description:The goat of this project is to explore lncRNA55666 efffect on small RNA to regulation goat mammary gland lipid metabolism. We tried to search the mechanism of lncRNA55666 regulation lipid metabolism through miRNA. small RNA seqencing of goat mamamary gland cells samples from different groups: 5NC, lncRNA55666 overexpression, 3NC, lncRNA55666 knockdown. The goat mammary gland cells were cultured in 3D condition. The cell were transfected with virus with lncRNA55666 gene (overexpression), or inhibition of lncRNA expression (lncRNA gene knockdown).
