Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Francisella tularensis subsp. novicida strain:KKF768

ABSTRACT: Francisella tularensis subsp. novicida strain:KKF768 Genome sequencing

PROVIDER: PRJNA1009449 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

Intra-macrophage Expression data of Francisella tularensis novicida U112

Project description:These samples are part of an experiment comparing the expression profiles of Francisella tularensis novicida grown in chemically defined medium and bacteria isolated 24 hours post infection of J774 macrophages to identify virulence factors

2017-05-02 | GSE75689 | GEO

Francisella tularensis subsp. novicida U112

Project description:Francisella tularensis subsp. novicida sRNA sequencing

| PRJNA314067 | ENA

Francisella tularensis subsp. novicida strain:FAI

Project description:Francisella tularensis subsp. novicida strain: FAI Genome sequencing

| PRJNA244559 | ENA

Francisella tularensis subsp. novicida FSC159

Project description:Francisella tularensis subsp. novicida FSC159 Genome sequencing

| PRJNA73383 | ENA

Francisella tularensis subsp. novicida FSC160

Project description:Francisella tularensis subsp. novicida FSC160 Genome sequencing

| PRJNA73385 | ENA

Francisella tularensis subsp. novicida D9876

Project description:Francisella tularensis subsp. novicida D9876 Genome sequencing

| PRJNA235892 | ENA

Francisella tularensis subsp. novicida U112

Project description:Francisella tularensis subsp. novicida U112 Genome sequencing

| PRJNA236529 | ENA

Francisella tularensis subsp. novicida F6168

Project description:Francisella tularensis subsp. novicida F6168 Genome sequencing

| PRJNA236045 | ENA

Francisella tularensis subsp. novicida FSC595

Project description:Francisella tularensis subsp. novicida FSC595 Genome sequencing

| PRJNA73395 | ENA

In vivo screen of Francisella tularensis subsp. novicida mutants in sequence defined transposon library

Project description:We used an inhalation mouse model of infection to query a collection of 2149 mutants in a Francisella tularensis subsp. novicida background for genes required for growth, survival and systemic dissemination. A microarray-based genome-wide negative selection screen (Microarray tracking of transposon mutants = MATT) allowed us to monitor the behavior of transposon insertions in 1371 unique genes. Interestingly most of these genes persisted in lung and colonized liver and spleen. We found 44 (35%) genes negatively selected in lung and 81 (65%) genes negatively selected in liver and/or spleen. If negative selection in lung occurred, the attenuated mutants in general persisted at 24h after infection, disseminated to liver and/or spleen and appeared to be lost in lung after 48 to 72h of infection. These genes with a strong phenotype in lung but also potential for dissemination might be attractive vaccine or drug candidates. Keywords: Genome-Wide Negative Selection Screen

2008-12-31 | GSE11297 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data