Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

ABSTRACT: Transcriptomic data of NK cells in myasthenia gravis patients

PROVIDER: PRJNA1035806 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR26670619_1.fastq.gz	Fastqsanger.gz
	SRR26670619_2.fastq.gz	Fastqsanger.gz
	SRR26670620_1.fastq.gz	Fastqsanger.gz
	SRR26670620_2.fastq.gz	Fastqsanger.gz
	SRR26670621_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 14

Similar Datasets

Transcription profiling of thymus from myasthenia gravis patients

Project description:Identification of deregulated genes in the thymus of myasthenia gravis patients' subgroup.

2006-11-09 | E-MEXP-518 | biostudies-arrayexpress

miRNA in CD4+ T cells: control vs. patients with myasthenia gravis

Project description:To investigate the abnormal expression amount of microRNAs in T cells of patients with myasthenia gravis

2018-03-16 | GSE111870 | GEO

miRNA expression profiling of thymus samples from myasthenia gravis patients

Project description:Autoimmune myasthenia gravis (MG) is characterized by thymic abnormalities such as hyperplasia and thymoma. Thymus plays an important role in self-tolerance and is involved in initiation and progression of the disease. A large proportion of MG patient show the presence of ectopic germinal centers (GC) in thymus that are absent in normal individuals. However, the exact mechanism how this change in thymus morphology is triggered and if this is related to pathophysiology of the disease remains unknown. In this study we have compared the mRNA profile of thymus samples obtained during a clinical trial (Thymectomy Trial in Non-Thymomatous Myasthenia Gravis Patients Receiving Prednisone Therapy. ClinicalTrials.gov Identifier: NCT00294658). We have compared the miRNA profile of thymus samples that have distinct germinal centers with those that lack them using Affymetrix miRNA array 4.0 to identify the differentially expressed genes with in the two groups.

2017-09-14 | GSE103812 | GEO

Proteomic profiling identifies ITIH3 as a biomarker for disease activity in myasthenia gravis

Project description:Myasthenia gravis (MG) is a chronic antibody-mediated autoimmune disease disrupting neuromuscular synaptic transmission. Antibodies (Abs) against the acetylcholine receptor (AChR) are detected in approximately 85% of patients. Here, we aimed to study the serum proteome of MG and to identify novel biomarkers reflecting disease activity.

2023-10-24 | PXD040786 | Pride

Project description:Fecal microbiota profile in myasthenia gravis patients

| PRJNA450610 | ENA

Muscle, normal extraocular, profile

Project description:Molecular definition of human extraocular muscles (EOM). Human EOM were compared with limb (quadriceps femoris) muscle. Keywords = Eye Keywords = EOM Keywords = Muscle Keywords = DMD Keywords = Myasthenia Gravis Keywords: other

2003-12-31 | GSE873 | GEO

Fungal gut microbiome in Myasthenia gravis: A sub-analysis of the MYBIOM study

Project description:Myasthenia gravis gut fungi

| PRJEB61825 | ENA

Gene expression profiling of thymus samples from myasthenia gravis patients.

Project description:Autoimmune myasthenia gravis (MG) is characterized by thymic abnormalities such as hyperplasia and thymoma. Thymus plays an important role in self-tolerance and is involved in initiation and progression of the disease. A large proportion of MG patient show the presence of ectopic germinal centers (GC) in thymus that are absent in normal individuals. However, the exact mechanism how this change in thymus morphology is triggered and if this is related to pathophysiology of the disease remains unknown. In this study we have compared the mRNA profile of thymus samples obtained during a clinical trial (Thymectomy Trial in Non-Thymomatous Myasthenia Gravis Patients Receiving Prednisone Therapy. ClinicalTrials.gov Identifier: NCT00294658). We have compared the mRNA profile of thymus samples that have distinct germinal centers with those that lack them using Affymetrix human transcriptome array 2.0 to identify the differentially expressed genes with in the two groups.

2017-09-19 | GSE103974 | GEO

Transcription factor NFAT1 regulates systemic autoimmunity through modulation of dendritic cell property

Project description:To characterize the roles of NFAT1 in the pathogenesis of autoimmune myasthenia gravis (MG) at a genome-wide scale, we performed gene expression microarray analysis for wild-type (WT) and NFAT1 KO bone marrow-derived dendritic cells (BMDCs) with or without 2h and 12h-stimulation with pam3CSK4.

2017-07-31 | GSE92593 | GEO

miRNA in CD4+ T cells: control vs. patients with myasthenia gravis

Project description:miRNA in CD4+ T cells: control vs. patients with myasthenia gravis

| PRJNA438450 | ENA