Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Transcriptomics of M0 macrophages treated with PTEN

ABSTRACT: Transcriptomics of M0 macrophages treated with PTEN

PROVIDER: PRJNA1048391 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

Transcriptomics of M0 macrophages treated with PTEN

Project description:While naive BMDMs without further treatment are referred to as M0-like macrophages, which can be polarized to either M1-like or M2-like macrophages,To assess the consequence of PTEN binding on macrophages, we profiled the global transcriptome of M0-like BMDMs with and without PTEN treatment.

2024-07-25 | GSE249264 | GEO

Transcriptomics of PLXDC2 knockdown BMDM treated with PTEN

Project description:To evaluate whether PLXDC2 mediated the role of PTEN on macrophages, PLXDC2 was knocked down in M2-polarized BMDMs, and the resultant PLXDC2-knocked down cells together with control cells were treated with or without PTEN, before subjected to global transcriptome profiling.

2024-07-25 | GSE249266 | GEO

Transcriptomics of PLXDC2 knockdown BMDM treated with PTEN

Project description:Transcriptomics of PLXDC2 knockdown BMDM treated with PTEN

| PRJNA1048389 | ENA

Glycoproteomics of human THP-1-derived M0, M1 and M2 macrophages

Project description:In this study, we used human THP-1-derived macrophages as an immune cell model, and systematically performed glycoproteomics of three subtypes of macrophages by StrucGP.To study the N‑Glycoproteomic of them, the intact glycopeptides were first enriched and identified using triplicate mass spectrometry (MS)-based glycoproteomic approaches, then StrucGP was used for subsequent analysis. In total three subtypes of macrophages, these intact glycopeptides consist of 253 N-linked glycan structures at 652 unique glycosites from 372 N-glycoproteins, along with their PSM information. A total of 135, 163, and 201 N-glycan structures were identified from M0, M1, and M2 macrophages, respectively.

2023-10-19 | PXD030277 | Pride

Transcriptomics of PTEN knockout B16-F10 cells in C57BL/6J mice model treated with PTEN

Project description:Transcriptomics of PTEN knockout B16-F10 cells in C57BL/6J mice model treated with PTEN

| PRJNA1047544 | ENA

Gene expression profiling of M0, M1 and M2a macrophages after 7 days of culture

Project description:The relative contribution of polarized macrophages to the maintenance of tolerance is unknown. We examined their roles by in vivo adoptive transfer immunotherapy of M0, M1 and M2a macrophages as pre-treatment of colitis. In other experiments, M2a macrophages were used as pre-treatment or treatment of established colitis followed by immunotherapy with nTreg cells. Survival, weight gain, tissue infiltration, iTreg and Th17 cell development, T cell activation, and the frequency of proinflammatory cytokines were used as outcome measurements. Pre-treatment with M2a but not M1 macrophages increased the development of iTreg and Th17 cells. M2a macrophages used as pre-treatment or in treatment of established colitis allowed for successful therapy with nTreg cells. M1 and M2a macrophages have distinct gene expression profiles. M0, M1 and M2a macrophages were cell sorted and were used to generate total RNA for each array set, which was labeled and hybridized to Affymetrix Mouse Genome 430 2.0 GeneChips in accordance to the manufacturerâ??s protocol. Three sets of arrays were performed, and the results were averaged. The subset of probe sets whose expression increased or decreased by two-fold or more relative to M0 cells as a common standard was identified and used for further analysis.

2016-03-02 | E-GEOD-72518 | biostudies-arrayexpress

Transcriptomic profile of M0 and M1 phenotype macrophages.

Project description:Transcriptomic profile of M0 and M1 phenotype macrophages.

| PRJNA916257 | ENA

Transcriptomics of PTEN knockout B16-F10 cells in C57BL/6J mice model treated with PTEN

Project description:extracellular PTEN treatment did not affect the growth of PTEN knockout B16-F10 cells cultured in vitro. , To investigate whether extracellular PTEN act on the tumor microenvironment to exert a tumor-suppressive role in vivo，molecular changes caused by PTEN treatment inside the B16-F10-PTEN tumors were monitored by RNA sequencing.

2024-07-24 | GSE249142 | GEO

Gene expression profiling of M0, M1 and M2a macrophages after 7 days of culture

2016-03-02 | GSE72518 | GEO

Transcriptomics of BMDM treated with PTEN in the presence or absence of STAT1 inhibitors

Project description:Transcriptomics of BMDM treated with PTEN in the presence or absence of STAT1 inhibitors

| PRJNA1048390 | ENA