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Effect of whole-body deletion of Gclc on the liver

ABSTRACT: Effect of whole-body deletion of Gclc on the liver

PROVIDER: PRJNA1096112 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR28551843.fastq.gz	Fastqsanger.gz
	SRR28551844.fastq.gz	Fastqsanger.gz
	SRR28551845.fastq.gz	Fastqsanger.gz
	SRR28551846.fastq.gz	Fastqsanger.gz
	SRR28551847.fastq.gz	Fastqsanger.gz

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Effect of whole-body deletion of Gclc on the liver

Project description:The rate-limiting step in glutathione (GSH) synthesis is controlled by glutamate-cysteine ligase catalytic subunit. To investigate the impact of GSH in vivo, we induced a deletion of Gclc using a Gclcf/f Rosa26-CreERT2 mouse model and harvested liver tissue for analysis.

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