Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

ABSTRACT: Spirochetes isolated from mosquitoes constitute a novel genus Entomospira genus novum

PROVIDER: PRJNA1121616 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR29330639_1.fastq.gz	Fastqsanger.gz
	SRR29330640_1.fastq.gz	Fastqsanger.gz
	SRR29330641_1.fastq.gz	Fastqsanger.gz
	SRR29330642_1.fastq.gz	Fastqsanger.gz
	SRR29330643_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 12

Similar Datasets

Entomospira genus nov

Project description:Spirochetes isolated from mosquitoes constitute a novel genus Entomospira genus novum within the order Spirochaetales

| PRJNA611537 | ENA

Project description:Spirochetes isolated from mosquitoes constitute a novel genus Entomospira genus novum within the order Spirochaetales

| PRJNA934383 | ENA

Epigenomic landscape of Lyme disease spirochetes reveals novel motifs

Project description:Epigenomic landscape of Lyme disease spirochetes reveals novel motifs

| PRJNA716641 | ENA

Project description:Anaerococcus spp. novum

| PRJNA851429 | ENA

Mouse skin samples after Zika virus-infected mosquito bites

Project description:Mouse skin bitten by Zika virus-infected mosquitoes were isolated and performed RNA-seq

2019-03-10 | GSE125194 | GEO

Malaria parasite hijacks host complement C3 to facilitate its transmission

Project description:Host-derived factors are sucked into midgut of mosquitoes during natural malaria transmission, but their influence on malaria transmission is largely unknown. We reported that mouse complement C3 taken into mosquitoes significantly promoted malaria transmission either in laboratory or in field. This effect was attributed to the reduction of microbiota abundance in mosquito midgut by host-derived C3 through direct lyses the predominant symbiont bacteria Elizabethkingia anopheles. Elizabethkingia anopheles symbiont bacteria were demonstrated to be detrimental to malaria sexual stages in mosquitoes. Strikingly, the promoted effect of host C3 on malaria transmission was confirmed by laboratory mosquitoes membrane-feeding on Plasmodium falciparum. Therefore, we reveal a novel strategy of malaria parasite to utilize host complement C3 to promote its transmission, and the administration of C3 inhibitor would provide us a novel strategy to control malaria transmission.

2024-08-01 | GSE271070 | GEO

Sex-specific transcriptomic response of Anopheles gambiae to O'nyong Nyong virus infection

Project description:O’nyong’nyong virus (ONNV) is an arbovirus of the genus Alphavirus which is transmitted to humans primarily by mosquitoes of the genus Anopheles. Here, An. stephensi males and females have been infected with ONNV to investigate their differential transcriptional response to infection. Males and female An. gambiae were injected with either a suspension of ONNV or sterile medium as a control and underwent pooled RNA extraction at 2- and 7-days post infection (DPI). Differential expression will be performed on pooled RNA samples to determine which genes are differentially regulated between males and females in response to infection, and which genes are activated or repressed in each sex as infection progresses. Further, genes identified as being regulated by infection or that differ in expression between males and females will be used to perform gene ontology (GO) analysis to determine what pre-identified gene sets are regulated under the scenarios being examined.

2024-12-31 | GSE175395 | GEO

Searching for new molecules involved in Anopheles mosquitoes’ response to Plasmodium infection

Project description:Plasmodium parasites within mosquitoes are exposed to various physiological processes, such as blood meal digestion activity, the gonotrophic cycle, and host responses preventing the entry of parasites into the midgut wall. However, when in vitro-cultured ookinetes are injected into the hemocoel of mosquitoes, Plasmodium parasites are not affected by the vertebrate host’s blood contents and do not pass through the midgut epithelial cells. This infection method might aid in identifying mosquito-derived factors affecting Plasmodium development within mosquitoes. This study investigated novel mosquito-derived molecules related to parasite development in Anopheles mosquitoes. We injected in vitro-cultured Plasmodium berghei (ANKA strain) ookinetes into female and male Anopheles stephensi (STE2 strain) mosquitoes and found that the oocyst number was significantly higher in males than in females, suggesting that male mosquitoes better support the development of parasites. Next, RNA-seq analysis was performed on the injected female and male mosquitoes to identify genes exhibiting changes in expression. Five genes with different expression patterns between sexes and greatest expression changes were identified as being potentially associated with Plasmodium infection. Two of the five genes also showed expression changes with infection by blood-feeding, indicating that these genes could affect the development of Plasmodium parasites in mosquitoes.

2024-05-06 | GSE197159 | GEO

Pleomorphic Variants of Borreliella (syn. Borrelia) burgdorferi Express Evolutionary Distinct Transcriptomes

Project description:The objective of the study was to uncover the transcriptional differences between B. burgdorferi pleomorphic forms (spirochetes, round bodies, blebs and biofilms).

2023-03-17 | GSE199941 | GEO

Flammeovirgaceae novel genus

Project description:Flammeovirgaceae novel genus genome sequencing

| PRJNA901263 | ENA