Ontology highlight
ABSTRACT:
PROVIDER: PRJNA1178375 | ENA |
REPOSITORIES: ENA
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Project description:Vibrio alginolyticus is a Gram-negative marine bacterium. A limited population of the organisms causes acute gastroenteritis in humans. In this study, Vibrio alginolyticus wild type strain EPGS is compared with the mutants of Ser-Thr kinase PpkA and phosphatase PppA, after cultured for 7h, in Luria-Bertani containing medium 3 % NaCl at 30 C. Our goal is to determine the ppkA and pppA regulon. Three wild type and five mutant Vibrio alginolyticus samples were compared.
2011-12-31 | E-GEOD-24319 | biostudies-arrayexpress
Project description:Vibrio alginolyticus is a Gram-negative marine bacterium. A limited population of the organisms causes acute gastroenteritis in humans. In this study, Vibrio alginolyticus wild type strain EPGS is compared with the mutants of Ser-Thr kinase PpkA and phosphatase PppA, after cultured for 7h, in Luria-Bertani containing medium 3 % NaCl at 30 C. Our goal is to determine the ppkA and pppA regulon.
2011-12-31 | GSE24319 | GEO
Project description:In recent years, due to the influence of climate change and rising sea temperature, the incidence of Vibrio alginolyticus infections is increasing, and becoming the second most common Vibrio species reported in human illness. Therefore, better understanding of the pathogenic mechanism of V. alginolyticus infection is urgently needed. Vvrr1 (Vibrio virulence regulatory RNA 1) is a new found ncRNA predicted to be closely related to the adhesion ability of V. alginolyticus through the previous RNA-seq. In this study, the target genes of Vvrr1 were fully screened and verified by constructing Vvrr1 over-expressed strains and proteome sequencing technology.
2020-05-26 | PXD014375 | Pride
Project description:Vibrio alginolyticus strain:shrimp | isolate:shrimp Genome sequencing
| PRJNA842900 | ENA
Project description:Vibrio species distribute ubiquitously in marine and coastal environments, with implications for severe infectious diseases in human and marine animals. However, precisely what defensive strategies the host employ against Vibrio pathogens with distinct virulence remain poorly understood. Being an ecologically relevant host, the oyster Crassostrea hongkongensis serves as an excellent model for elucidating mechanisms underlying host-Vibrio interactions. In this study, we generated one mutant Vibrio alginolyticus strains (V. alginolyticus△VSCC) with attenuated virulence by knocking out the VSCC encoding gene, one of the core components of type III secretion systems (T3SSs), based on the evidence that V. alginolyticus△VSCC infection leads to a marked reduction in the apoptotic rate of hemocyte hosts, compared to V. alginolyticusWT control. In comparative proteomics, it was revealed that distinct immune responses were elicited upon encounter with V. alginolyticus strains of different virulence. Quite strikingly, the peroxisomal and apoptotic pathways are activated by V. alginolyticusWT infection, whereas phagocytosis and cell adhesion were enhanced in V. alginolyticus△VSCC infection. Collectively, we conclude that adaptation in host immune responses is determined in part by pathogen virulence, which safeguards elimination of invading bacteria in efficient and timely manners.
2022-02-16 | PXD022551 | Pride
Project description:The heterogeneity of bacterial cells in biofilms is an important property. We performed single-cell sequencing to profile heterogeneous cell populations within Vibrio alginolyticus biofilm. Our analysis has revealed the key functional compartments for the composition and development of biofilms
2024-10-27 | GSE280047 | GEO
Project description:MiRNA sequencing of shrimp stimulated by Vibrio alginolyticus
| PRJNA761657 | ENA
Project description:Vibrio campbellii BAA-1116 was used as a Harveyi clade model organism to determine the impact of indole signaling on virulence. Gene expression analysis of V. campbellii grown in LB35 broth with or without 100 μM indole revealed that indole decreased: (1) V. campbellii virulence in shrimp and prawn challenge assays, (2) exopolysaccharide production, and (3) swimming motility. The results also indicated that indole inhibits quorum sensing-regulated bioluminescence and blocks the three-channel quorum sensing system by interfering with quorum sensing signal transduction.
2016-10-31 | GSE80484 | GEO
Project description:Comparative proteomics analysis of type VI secretion-dependent secretomes of Vibrio alginolyticus 12G01
2014-11-21 | MSV000078946 | MassIVE