Project description:The razor clam Sinonovacula constricta (Lamarck 1818) is a famous marine bivalve species that widely distributed along the western Pacific coast with important economical and nutritional values. During the evolution, S. constricta has formed specific biological features to adapt to its living habit. To clarify the underlying molecular mechanism in forming the specific biological features, the tissues of siphon, gill, labial palp, foot, mantle, and intestine of S. constricta were subjected to RNA-sequencing. The results showed significant differences existed in gene expression among different tissues, which provided a molecular framework for understanding the differentiation of S. constricta tissues and their underlying specific biological functions.
2023-07-02 | GSE235883 | GEO
Project description:Evolution of the mitochondrial genome in gymnosperms
Project description:The Manila clam (Ruditapes philippinarum) is a cultured bivalve species with high worldwide commercial importance. Nevertheless, diseases can cause high economical losses. For this reason, the study of immune genes in bivalve mollusks has increased in the last years. The present work describes the construction of the first R. philippinarum microarray containing immune-related hemocyte sequences and its application for the study of the gene transcription profiles of hemocytes from clams challenged with Vibrio alginolyticus through a time course.
Project description:We produced differentially sensitive-temperature phenotypes using genetically defined larval families of the bivalve Crassostrea gigas. Larval growth rates varied ~5-fold and reciprocal hybrids showed different genotype-dependent responses over a 15-25°C temperature range. Whole-genome expression analysis of ~24 million cDNAs from larvae identified 22,250 unique transcripts. Of these, ~15% showed a significant interaction between genotype and temperature and are associated with genotype-dependent differences in response to temperature.
Project description:ChIP-seq data characterizing the occupancy of TFAM over the mitochondrial and nuclear genomes in HeLa cells. Characterization of mitochondrial and nuclear genome-wide TFAM binding in HeLa cells