Project description:Chromatin, in addition to its purely structural functions, is considered a major regulatory system coordinating various genetic networks in eukaryotes. Constant changes of gene expression programs are especially important for plants, which have to respond to environment by modulating their growth and development during whole lifetime. External and developmental signals can be transmitted through signaling cascades to chromatin remodeling complexes like SWI/SNF, which alter chromatin structure by moving, ejecting or restructuring nucleosomes. Genetic studies in Arabidopsis thaliana revealed that SWI/SNF chromatin remodeling complexes are critical for proper plant development and growth. Especially, BRM, a catalytic subunit of the complex, was shown to directly regulate several genes with important functions in leaf development, flowering initiation, as well as gibberellin and abscisic acid signaling. In this study, we profiled BRM global binding regions in Arabidopsis genome by ChIP-chip analysis. We found that BRM can bind to thousands of genes, many of which have key functions in hormone and stress signaling.

2016-12-20 | GSE71656 | GEO

E-GEOD-47735

Project description:Interplay of host microbiota, genetic perturbations, and inflammation promote local development of intestinal neoplasms in mice

2019-05-14 | E-GEOD-47735 | ExpressionAtlas

Arabidopsis thaliana

Project description:Time-resolved transcriptome analysis with genetic perturbations reveals a critical time window for effective plant immunity

| PRJNA348676 | ENA

Arabidopsis thaliana

Project description:Genetic influences on gene expression in Arabidopsis thaliana

| PRJNA358059 | ENA

Arabidopsis thaliana

Project description:Auxin Response Factor mediated flower gene expression

| PRJNA91905 | ENA