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Homo sapiens strain:(KHV) Kinh in Ho Chi minh City, Vietnam

ABSTRACT: CompleteGenomics sequencing of (KHV) Kinh in Ho Chi minh City, Vietnam

PROVIDER: PRJNA177965 | ENA |

REPOSITORIES: ENA

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			Action	DRS
		Other
	SRR576691_1.fastq.gz	Fastqsanger.gz
	SRR576691_2.fastq.gz	Fastqsanger.gz
	SRR576692_1.fastq.gz	Fastqsanger.gz
	SRR576692_2.fastq.gz	Fastqsanger.gz

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Homo sapiens strain:(KHV) Kinh in Ho Chi minh City, Vietnam

Project description:CompleteGenomics sequencing of (KHV) Kinh in Ho Chi minh City, Vietnam. DNA for sequencing was extracted from whole blood

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Homo sapiens strain:(KHV) Kinh in Ho Chi minh City, Vietnam

Project description:Whole genome sequencing of (KHV) Kinh in Ho Chi minh City, Vietnam. DNA for sequencing was extracted from whole blood

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The dynamics of GII.4 Norovirus in Ho Chi Minh City, Vietnam.

Project description:Norovirus (NoV) is a major cause of epidemic gastroenteritis in industrialized countries, yet the epidemiological significance of NoV in industrializing countries remains poorly understood. The spatiotemporal distribution of NoV genotypes identified in 2054 enrolled children was investigated between May 2009 and December 2010, in Ho Chi Minh City (HCMC), Vietnam. A total of 315 NoV extracted from stool samples were genotyped and GPS mapped to their source. Genogroup II NoV, particularly GII.4, were predominant, and the GII.4 strains could be subgrouped into GII.4-2006b (Minerva) and GII.4-2010 (New Orleans) variants. There was no spatiotemporal structure among the endemic GII strains; yet a significant spatiotemporal signal corresponding with the novel introduction of GII.4-2010 variant was detected. These data show that NoV GII.4 variants are highly endemic in HCMC and describe a scenario of rapid NoV strain replacement occurring in HCMC in early 2010.

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Endemic norovirus infections in children, Ho Chi Minh City, Vietnam, 2009-2010.

Project description:We performed a case-control investigation to identify risk factors for norovirus infections among children in Vietnam. Of samples from 1,419 children who had diarrhea and 609 who were asymptomatic, 20.6% and 2.8%, respectively, were norovirus positive. Risk factors included residential crowding and symptomatic contacts, indicating person-to-person transmission of norovirus.

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Project description:Enterovirus 71 (EV71) frequently causes fatal infections in young children in Asia. In 2011, EV71 epidemics occurred in southern Vietnam. We conducted genetic and antigenic analysis of the EV71 isolates and found that 94% of them were genotype C4a related to two lineages circulating in China and 6% were genotype C5 which have circulated in Vietnam since 2003. Antigenic variants were not detected. EV71 vaccines are being developed. Longitudinal enterovirus surveillance data are critical to formulate vaccination policy in Vietnam.

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