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Schizosaccharomyces pombe

ABSTRACT: Yeast X-Chromosome Associated Protein 5 (Xap5) Functions with H2A.Z to Suppress Aberrant Transcripts [RNA-seq]

PROVIDER: PRJNA198902 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR13106214.fastq.gz	Fastqsanger.gz
	SRR13106215.fastq.gz	Fastqsanger.gz
	SRR13106216.fastq.gz	Fastqsanger.gz
	SRR13218621.fastq.gz	Fastqsanger.gz
	SRR13218626.fastq.gz	Fastqsanger.gz

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Schizosaccharomyces pombe

Project description:Yeast X-Chromosome Associated Protein 5 (Xap5) Functions with H2A.Z to Suppress Aberrant Transcripts [ChIP-chip]

| PRJNA200697 | ENA

Project description:Yeast X-Chromosome Associated Protein 5 (Xap5) Functions with H2A.Z to Suppress Aberrant Transcripts

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Yeast X-Chromosome Associated Protein 5 (Xap5) Functions with H2A.Z to Suppress Aberrant Transcripts [ChIP-chip]

Project description:Comparison of occupancy profiling of Xap5 and H2A.Z/Pht1 in fission yeast. Agilent 60mer array was used to analyze DNA recovered by chromatin immunoprecipitation of Xap5 from fission yeast culture.

2014-07-01 | E-GEOD-46505 | biostudies-arrayexpress

Schizosaccharomyces pombe

Project description:Histone H2A.Z cooperates with RNAi and heterochromatin factors to suppress antisense RNAs

| PRJNA119129 | ENA

Yeast X-Chromosome Associated Protein 5 (Xap5) Functions with H2A.Z to Suppress Aberrant Transcripts [ChIP-chip]

Project description:Comparison of occupancy profiling of Xap5 and H2A.Z/Pht1 in fission yeast.

2014-07-01 | GSE46505 | GEO

Schizosaccharomyces pombe

Project description:Epigenetically induced paucity of histone H2A.Z stabilizes fission yeast ectopic centromeres

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XCT is a novel regulator of chromatin functionally conserved across eukaryotes

Project description:XCT was originally identified due to the short circadian period observed in plants mutant for this gene. Proteins with homology to XCT are found across eukaryotes, but their molecular function is unknown. We have recently demonstrated that in Schizosaccharomyces pombe, the XCT ortholog Xap5 is a chromatin-associated protein that acts in a similar manner as the histone variant H2A.Z to suppress aberrant gene expression. Here, we demonstrate that although XCT and H2A.Z act in similar pathways to control plant development, XCT's role in the circadian clock is independent of H2A.Z.

2019-05-01 | GSE67813 | GEO

Comparison of RNA profiling between wild type, med20∆, rrp6∆ and med20∆/rrp6∆ in Schizosaccharomyces pombe

Project description:Mediator is a co-regulator of RNA polymerase II (Pol II), transducing signals from regulatory elements and transcription factors to the general transcription machinery at the promoter. We here demonstrate that Med20 influences ribosomal protein expression in fission yeast. In addition, loss of Med20 leads to an accumulation of aberrant readthrough tRNA transcripts. The aberrant transcripts are polyadenylated and targeted for degradation by the exosome. Similarly, other specialized RNA molecules, such as snRNA, snoRNA and rRNA are also accumulated in the absence of Med20. We suggest that fission yeast Mediator takes part in a regulatory pathway of Pol III transcripts.

2016-01-01 | GSE73792 | GEO

Schizosaccharomyces pombe

Project description:Meiotic cohesins modulate chromosome compaction during meiotic prophase in fission yeast

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Comparison of RNA profiling between wild type, med20â, rrp6â and med20â/rrp6â in Schizosaccharomyces pombe

Project description:Mediator is a co-regulator of RNA polymerase II (Pol II), transducing signals from regulatory elements and transcription factors to the general transcription machinery at the promoter. We here demonstrate that Med20 influences ribosomal protein expression in fission yeast. In addition, loss of Med20 leads to an accumulation of aberrant readthrough tRNA transcripts. The aberrant transcripts are polyadenylated and targeted for degradation by the exosome. Â Similarly, other specialized RNA molecules, such as snRNA, snoRNA and rRNA are also accumulated in the absence of Med20. We suggest that fission yeast Mediator takes part in a regulatory pathway of Pol III transcripts. RNA-sequencing of wt, med20â, rrp6â, med20â/rrp6â strains using wt as control. Each strain was sequenced using three biological replicas. The results were analyzed for differential expression.

2016-07-03 | E-GEOD-73792 | biostudies-arrayexpress

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