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Mus musculus

ABSTRACT: H3K4me3 chromatin profiling in SUMOylation-competent and -deficient bone marrow derived dendritic cells unstimulated or stimulated with LPS

PROVIDER: PRJNA276565 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR1820760.fastq.gz	Fastqsanger.gz
	SRR1820761.fastq.gz	Fastqsanger.gz
	SRR1820756.fastq.gz	Fastqsanger.gz
	SRR1820757.fastq.gz	Fastqsanger.gz
	SRR1820758.fastq.gz	Fastqsanger.gz

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Project description:SUMO and RNAPolII chromatin profiling in SUMOylation-competent and -deficient bone marrow derived dendritic cells unstimulated or stimulated with LPS

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H3K4me3 chromatin profiling in SUMOylation-competent and -deficient bone marrow derived dendritic cells unstimulated or stimulated with LPS

Project description:Purpose: To determine H3K4me3 chromatin profile in UBC9WT and UBC9KO BMDC before and after LPS stimulation. Methods: H3K4me3 chromatin profile was determined by sequencing UBC9 WT and UBC9 KO BMDC chromatin immunoprecipitated with antibody specific for H3K4me3. Results: We show differential chromatin profile for H3K4me3 on the ifnb1 locus between UBC9 KO cells and UBC9 WT. Conclusions: Loss of SUMOylation causes a deregulation of ifnb1 transcription activation mark. A study of H3K4me3 chromatin profile in UBC9 WT and UBC9 KO Bone Marrow derived Dendritic Cells.

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