Project description:S288C was transformed with plasmids expressing the GCN5 F221A mutant at varying levels. We sought to examine the global impact on gene expression using the Affymetrix yeast 2.0 arrays.
Project description:The study on the effect of nitrogen replenishment on the gene expression following a rapamycin treatment showed that the down-regulation of the glycolytic transcripts was generally suppressed after this treatment. This indicated that the TOR signaling pathway likely controls the expression of the glycolytic gene under these conditions.