Project description:Maternal chromium restriction may disturb susceptibility in offspring. Adipose from maternal chromium diet has 1214 CpG sites that exhibit differential DNA methylationregulated compared to control. We performed DNA methylation array analyses of offspring adipose from chromium restriction dams and control diet dams at 32 week (n=3 per group).
Project description:Maternal chromium restriction may disturb susceptibility in offspring. Liver from maternal chromium diet has 8 up- and 6 down- regulated miRNAs, compared to control.
Project description:Maternal chromium restriction may disturb susceptibility in offspring. Liver from maternal chromium diet has 264 up- and 199 down- regulated genes, compared to control. Especially, Insulin signaling pathway and WNT pathway were affected.