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Streptomyces

ABSTRACT: Isolates belonging to the genus Streptomyces - Raw sequence reads

PROVIDER: PRJNA340269 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR4101760.fastq.gz	Fastqsanger.gz
	SRR4101770.fastq.gz	Fastqsanger.gz
	SRR4101761.fastq.gz	Fastqsanger.gz
	SRR4101771.fastq.gz	Fastqsanger.gz
	SRR4101772.fastq.gz	Fastqsanger.gz

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Streptomyces

Project description:Isolates from the genus Streptomyces. Raw sequence reads

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Global gene transcription analysis in response to changes in chromosome supercoiling in Streptomyces coelicolor

Project description:Here, we address the transcriptional response to both novobiocin-induced rapid chromosome relaxation or long-term topological imbalance, both increased and decreased supercoiling, in environmental antibiotic-producing bacteria belonging to the Streptomyces genus.

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Global gene transcription analysis in response to changes in chromosome supercoiling in Streptomyces coelicolor

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Two-component signal transduction systems in Streptomyces and related organisms

Project description:Two component sensor-response regulator systems (TCSs) are very common in the genomes of the Streptomyces species that have been fully sequenced to date. It has been suggested that this large number is an evolutionary response to the variable environment that Streptomyces encounter in soil. Notwithstanding this, TCSs are also more common in the sequenced genomes of other Actinomycetales when these are compared to the genomes of most other eubacteria. In this study, we have used DNA/DNA genome microarray analysis to compare fourteen Streptomyces species and one closely related genus to Streptomyces coelicolor in order to identify a core group of such systems. This core group is compared to the syntenous and non-syntenous TCSs present in the genome sequences of other Actinomycetales in order to separate the systems into those present in Actinomycetales in general, the Streptomyces specific systems and the species specific systems. Horizontal transfer does not seem to play a very important role in the evolution of the TCS complement analyzed in this study. However, cognate pairs do not necessarily seem to evolve at the same pace, which may indicate the evolutionary responses to environmental variation may be reflected differently in sequence changes within the two components of the TCSs. The overall analysis allowed subclassification of the orphan TCSs and the TCS cognate pairs and identification of possible targets for further study using gene knockouts, gene overexpression, reporter genes and yeast two hybrid analysis.

2009-01-31 | GSE13621 | GEO

Streptomyces secondary metabolism

Project description:This project aims to discover novel bioactive compounds from Streptomyces isolated from the rhizosphere from wild medicinal plants from Hamedan province, Iran. Proteomics is used to assist in discovery and characterization of the compounds. Streptomyces isolates are grown on ISP-4 medium for three days, proteins were extracted and analysed by shotgun proteomics.

2024-01-04 | PXD041994 | Pride

Morus alba Raw protein sequence reads

Project description:Morus alba L. Raw protein sequence reads and sequence

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Streptomyces secondary metaboites - strain M1

Project description:In this study, we describe the isolation and identification of Streptomyces isolates collected from traditional medicinal plants’ rhizosphere during a campaign in Hamedan Province, Iran. Traditional medicinal plants represent a rich and unique source for the isolation of Streptomyces and new antimicrobial compounds. This strain was isolated from the rhizosphere of Helichrysum rubicundum

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Analysis the Ability of Producing Secondary Metabolites of Streptomyces bingchenggensis By The Genome Sequence and GeneChip DNA microarrays

Project description:Streptomyces bingchenggensis is a soil bacterium that produces a family of macrolide antibiotics, milbemycins, which is commercially important in crop protection, human and veterinary medicine. After the complete genome sequence, and annotation, for further development of our gene expression approach to biosynthesis, we have employed whole genome microarray expression profiling as a discovery platform to obtain improved specificity and sensitivity of gene expression analysis, allowing a global and at the same time detailed picture of how gene clusters for secondary metabolism are modulated. In the result, we confirmed the expression mil and nan gene cluster, furthermore, pks3, pks5 and nrps7, nrps8 also showed significant gene expression, but no obvious products detected. In Streptomyces bingchenggensis, there are also corresponding genes belonging to Defense mechanisms, which is much more than other Streptomyces, for the resistance of own metabolites and dealing with complex environmental factors.

2011-09-20 | GSE32205 | GEO

Streptomyces sp.

Project description:Streptomyces Raw sequence reads

| PRJNA394798 | ENA

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Project description:Streptomyces atratus Raw sequence reads

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