Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Extensive Functional Redundancy of Mammalian Enhancers

ABSTRACT: Extensive Functional Redundancy of Mammalian Enhancers

PROVIDER: PRJNA362215 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR5182420.fastq.gz	Fastqsanger.gz
	SRR5182430.fastq.gz	Fastqsanger.gz
	SRR5182440.fastq.gz	Fastqsanger.gz
	SRR5182450.fastq.gz	Fastqsanger.gz
	SRR5182460.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 52

Similar Datasets

Extensive Functional Redundancy of Mammalian Enhancers [RNA-seq]

Project description:Analysis of the transcriptional changes in the limb resulting from the loss Gli3 limb enhancers

2018-01-01 | GSE93729 | GEO

Extensive Functional Redundancy of Mammalian Enhancers

Project description:This SuperSeries is composed of the SubSeries listed below.

2018-01-01 | GSE93730 | GEO

Mus musculus

Project description:Extensive Functional Redundancy of Mammalian Enhancers [ChIP-seq]

| PRJNA362213 | ENA

Mus musculus

Project description:Extensive Functional Redundancy of Mammalian Enhancers [RNA-seq]

| PRJNA362218 | ENA

Extensive Functional Redundancy of Mammalian Enhancers [ChIP-seq]

Project description:Analysis of the epigenomic landscape in limbs of homozygous limb enhancer knockout mice

2018-01-01 | GSE93728 | GEO

Proteome-Level Functional Redundancy in the Human Gut Microbiome

Project description:Here, we quantify the proteome-level functional redundancy in the human gut microbiome using metaproteomics and network approaches.In particular, we used an ultra-deep metaproteomics approach based on high-pH reverse phase fractionation. The data analysis revealed high protein-level functional redundancy and high nestedness in proteomic content networks - bipartite graphs that connect taxa with their expressed functions.

2023-06-08 | PXD027297 | Pride

Early and extensive venous arterialization during mammalian embryogenesis

Project description:Early and extensive venous arterialization during mammalian embryogenesis

| PRJNA374719 | ENA

Identification of H3 Lysine 4 Monomethylation Associated Proteins at Mammalian Enhancers

Project description:Enhancers act to regulate cell type specific gene expression by facilitating the transcription of target genes. In mammalian cells active or primed enhancers are commonly marked by monomethylation of Histone H3 at lysine 4 (H3K4me1) in a cell-type specific manner. Whether and how this histone modification regulates enhancer-dependent transcription programs in mammals has been unclear. In the present study, we conducted SILAC Mass-spec experiments with mono-nucleosomes and identified multiple H3K4me1 associated proteins, including proteins involved in chromatin remodeling. We demonstrate that H3K4me1 augments the association of the chromatin remodeling complex BAF to enhancers in vivo. Furthermore we show that in vitro, H3K4me1 nucleosomes are more efficiently remodeled by the BAF complex. Crystal structures of a BAF component BAF45c further reveal that monomethylation, but not trimethylation, is accommodated in this protein’s H3K4 binding site. Our results suggest that H3K4me1 plays an active role at enhancers by facilitating the binding of the BAF complex and possibly other chromatin regulators.

2018-10-23 | PXD007942 | Pride

Functional enhancers shape extrachromosomal oncogene amplifications

Project description:Functional enhancers shape extrachromosomal oncogene amplifications

| PRJNA579579 | ENA

Functional redundancy of variant and canonical histone H3K9 modification in Drosophila

Project description:Functional redundancy of variant and canonical histone H3K9 modification in Drosophila

| PRJNA415844 | ENA