ABSTRACT: Dynamics of resistance plasmids in extended spectrum beta-lactamase-producing Enterobacteriaceae in the gut microflora of patients during 1 year post UTI.
Project description:The present study examines changes in global gene expression patterns and in virulence factor-associated genes in an extended spectrum beta-lactamase (ESBL)-producing UPEC (ESBL019) during the morphologic transitions induced by an ineffective antibiotic and in the presence of human primary bladder epithelial cells. The morphological shifts induced by ineffective antibiotics are associated with significant transcriptional virulence alterations in ESBL-producing UPEC, which may affect survival and persistence in the urinary tract.
2017-06-06 | GSE99661 | GEO
Project description:Genomic characterization of extended-spectrum beta-lactamase-producing and carbapenem-resistant Enterobacteriaceae isolated from urban Wastewater
| PRJNA916637 | ENA
Project description:Genome sequences of extended-spectrum beta-lactamase producing Escherichia coli.
