Project description:The present microarray studies the differential transcription levels of various genes upon overexpression of tumor suppressor protein SMAR1. The results will lead us to potential targets which are either up/downregulated by SMAR1.
Project description:To futher find the gene expression due to the aromatase overexpression in the mouse testis,we have employ whole genome microarray expression profiling as a discovery platform to identify genes compared to the wild type mice. The testes were taken from 5 month old aromatase overexpression mice and WT mice as control.
Project description:To reveal the changes of miRNAs levels in HCT116 cells with METTL14 overexpression, we employed miRNA microarray expression profiling in HCT116 human colon cancer cells stably expressing control vector or METTL14.
Project description:To investigate the target genes of FHL3 in glioma cells, we conducted a gene expression microarray analysis to identify novel FHL3 regulating genes. The FHL3 overexpressed T98G glioma cells l were used as the experiments model. We conservatively established a minimum of 2-fold difference between FHL3 and control group, with an FDR-adjusted P value of less than 0.05, and identified 285 up-regulated and 420 down-regulated genes that met the threshold in all microarray analyses of 3 independent groups.
