Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

RNA-seq analysis of transcriptomes of Noc4L deficient and the Nco4L sufficient Treg cells

ABSTRACT: RNA-seq analysis of transcriptomes of Noc4L deficient and the Nco4L sufficient Treg cells

PROVIDER: PRJNA479423 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR7467163.fastq.gz	Fastqsanger.gz
	SRR7467164.fastq.gz	Fastqsanger.gz
	SRR7467165.fastq.gz	Fastqsanger.gz
	SRR7467166.fastq.gz	Fastqsanger.gz
	SRR7467167.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 6

Similar Datasets

RNA-seq analysis of transcriptomes of Noc4L deficient and the Nco4L sufficient Treg cells

Project description:To gain in depth transcriptional information about the Noc4L deficient and Noc4L sufficient Tregs, we performed RNA-seq analysis to compare the transcriptomes of Noc4L deficient (CD4+GFP+CD62Lhigh, cKO) and Noc4L sufficient (CD4+GFP+CD62Lhigh, Het) Tregs activated in vitro with Dynabeads for 48 hours or 72 hours. We found ~25 unique genes with differential expression between the Noc4L deficient and Noc4L sufficient Treg cells when activated for 48 hours in vitro. And ~100 unique genes with differential expression between the Noc4L deficient and Noc4L sufficient Treg cells when activated for 72 hours in vitro in two times experiment.

2018-07-04 | GSE116572 | GEO

Transcriptome analysis of OGT-sufficient and OGT-deficient regulatory T (Treg) cells

Project description:Transcriptome analysis of OGT-sufficient and OGT-deficient regulatory T (Treg) cells

| PRJNA480070 | ENA

Transcriptome analysis of OGT-sufficient and OGT-deficient regulatory T (Treg) cells

Project description:To gain comprehensive insight into the OGT-dependent transcriptional program in Treg cells, we performed RNA-sequencing of isolated YFP+ Treg cells from Foxp3YFP-Cre/wtOgtwt/fl and healthy Foxp3YFP-Cre/wtOgtfl/fl females to avoid secondary changes in gene expression caused by inflammation. We were able to identify 269 differentially expressed genes including 154 downregulated and 115 upregulated with p values less than 0.01, OGT-deficient Treg cells had impaired suppressive function and attenuated IL2/STAT5 signaling pathway.

2018-12-21 | GSE116758 | GEO

Gene expression profile at single cell level of Treg cells (CD4+CD25+) from healthy Mycfl/flFoxp3Cre/WT female mice, in which Myc-sufficient (WT) and Myc-deficient (KO) Treg cells co-exist

Project description:We performed single cell transcriptome analysis of Treg cells (CD4+CD25+) from healthy Mycfl/flFoxp3Cre/WT female mice, in which Myc-sufficient (WT) and Myc-deficient (KO) Treg cells co-exist due to random inactivation of the X chromosome that harbors the Foxp3 gene.

2022-07-17 | GSE208252 | GEO

Transcriptomic analysis of mouse splenic B cells that are either TG2-sufficient or TG2-deficient

Project description:To compare the transcriptomes of TG2-sufficient and TG2-deficient mouse splenic B cells under resting and stimulated conditions.

2019-11-08 | E-MTAB-7567 | biostudies-arrayexpress

RNA sequence analysis between ECM1- sufficient and -deficient peritoneal macrophage

Project description:RNA sequence analysis between ECM1- sufficient and -deficient peritoneal macrophage

| PRJNA590877 | ENA

Foxo1/3-deficient Treg cells

Project description:Identification of Foxos target genes in Treg cells. Foxo1and Foxo3 are transcription factors of Foxo family. CD4+Foxp3+ Treg cells isolated from wild-type and Foxo1/3-deficient mice were analyzed by global gene expression profiling. Results indicate Foxos regulate expression of a subset of Treg cell signature genes and genes in control of T cell homeostasis, signaling and metabolism. 2 sets wild-type and Foxo1/3-deficient CD4+Foxp3+ Treg cells

2010-09-13 | E-GEOD-21678 | biostudies-arrayexpress

Bulk RNA-Seq analysis of WT and Bach2-deficient Foxp3+ Treg cells

Project description:These are the FastQ files used for the RNA-seq analysis of WT and Bach2-deficient splenic Foxp3+ Treg cells.

2020-05-12 | GSE127699 | GEO

Analysis of transcriptomes of germinal center (GC) B cells derived from miR-155-sufficient and -deficient mice

Project description:Analysis of transcriptomes of germinal center (GC) B cells derived from miR-155-sufficient and -deficient mice

| PRJNA967244 | ENA

Single-cell RNA-Seq analysis of WT and Bach2-deficient Foxp3+ Treg cells

Project description:These are the FastQ files used for scRNA-Seq analysis of WT and Bach2-deficient splenic Foxp3+ Treg cells

2020-05-12 | GSE128175 | GEO