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RNA-seq of Splenic CD4+ T cells and colon epithelial cells from miR-34a-/- and wildtype mice

ABSTRACT: RNA-seq of Splenic CD4+ T cells and colon epithelial cells from miR-34a-/- and wildtype mice

PROVIDER: PRJNA509684 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR8314870.fastq.gz	Fastqsanger.gz
	SRR8314871.fastq.gz	Fastqsanger.gz
	SRR8314862.fastq.gz	Fastqsanger.gz
	SRR8314872.fastq.gz	Fastqsanger.gz
	SRR8314863.fastq.gz	Fastqsanger.gz

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RNA-seq of Splenic CD4+ T cells and colon epithelial cells from miR-34a-/- and wildtype mice

Project description:miR-34a is a known tumor suppressor that targets cell proliferation and apoptosis genes. In this study, we have shown that miR-34a acts as a safeguard for the inflammatory stem cell niche and reparative regeneration by modulating both the immune and epithelial responses to infection and inflammation. We isolated CD4+ T cells and colon epithelial cells from miR-34a-/- and wildtype mice revealed various changes in gene expression.

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Identification of SART3 as a pre-miR-34a–binding protein

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