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ABSTRACT: Barrett's esophagus microbiome with progression to EAC

PROVIDER: PRJNA517734 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR8503900_1.fastq.gz	Fastqsanger.gz
	SRR8503900_2.fastq.gz	Fastqsanger.gz
	SRR8503910_1.fastq.gz	Fastqsanger.gz
	SRR8503910_2.fastq.gz	Fastqsanger.gz
	SRR8503920_1.fastq.gz	Fastqsanger.gz

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Serum glycoprotein biomarker discovery and qualification pipeline reveals novel diagnostic biomarkers for esophageal adenocarcinoma

Project description:The aim of this project is to identify circulatory diagnostic glycoprotein biomarkers for Barrett's esophagus (BE) and esophageal adenocarcinoma (EAC). Serum samples from healthy, BE and EAC patients were screened using LeMBA-LC-MS/MS-GlycoSelector pipeline as described in the manuscript.

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Using DNA methylation to detect dysplasia/early neoplasia in Barrett's carcinogenesis

Project description:Dysplasia and early cancer are hard to detect in endoscopic biopsies and hence this study was carried out to evaluate the biomarker potential of DNA methylation to detect dyspasia and early cancer in Barrett's esophaghus patients. Bisulfite converted genomic DNA was hybridized onto Illumina 27k methylation arrays. 22 Barrett's esophagus (BE) and 2 Duodenum vs. 24 esophageal adenocarcinoma (EAC)

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