Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

MRNA expression profile in WT and ZNF598 knockout HeLa cells stimulated with short poly I:C

ABSTRACT: mRNA expression profile in WT and ZNF598 knockout HeLa cells stimulated with short poly I:C

PROVIDER: PRJNA539929 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

mRNA expression profile in WT and ZNF598 knockout HeLa cells stimulated with short poly I:C

Project description:mRNA expression profiles were compared between wild-type and ZNF598 knockout cells in the presence or absence of a RIG-I ligand, short poly I:C.

2019-07-30 | GSE130370 | GEO

Poly(A)-ClickSeq resolves CF25-mediated alternative poly-adenylation, HeLa

Project description:Poly(A)-ClickSeq is a new methodology for the sequencing of the 3'UTR/poly(A) tail junction of RNA. We analysed both wild-type and CF25Im knock-down HeLa cells in culture using Poly(A)-ClickSeq to find the distribution of poly(A) sites in these samples and determine the role of CF25Im in poly(A) site selection (alternative poly-adenylation, APA).

2017-05-02 | GSE94950 | GEO

ENCODE Transcript Mapping for Human HeLa Poly(A)+ RNA

Project description:Transcript Mapping on Affymetrix ENCODE arrays for 3 different biological replicates of HeLa Poly(A)+ RNA Keywords: other

2007-04-06 | GSE7437 | GEO

mRNA expression profile in LGP2 and LGP2-4KR transgenic (Tg) HEK293 cells stimulated with short poly I:C

Project description:mRNA expression profiles were compared between wild-type LGP2 and four amino acid replacement LGP2 (LGP2-4KR) cells in the presence or absence of a RIG-I ligand, short poly I:C.

2022-06-07 | GSE176363 | GEO

Global alteration of transcript decay rates upon ZNF598 knockdown

Project description:We calculated half-life of transcripts in HEK293T cells expressing control or ZNF598-targeting shRNA.

2024-07-11 | GSE233374 | GEO

mRNA expression profile in LGP2 and LGP2-4KR transgenic (Tg) HEK293 cells stimulated with short poly I:C

Project description:mRNA expression profile in LGP2 and LGP2-4KR transgenic (Tg) HEK293 cells stimulated with short poly I:C

| PRJNA736018 | ENA

STAT1 transcription factor in Human HeLa S3

Project description:We report the results of chromatin immunoprecipitation following by high-thoughput tag sequencing (ChIP-Seq) using the GA II platform from Illumina for the human transcription factor STAT1 in HeLa S3 cells. The STAT1 ChIP was performed using HeLa S3 cells that are stimulated using gamma-interferon. We have also generated a seqenced input DNA dataset for gamma-interferon stimulated HeLa S3 cells. Raw data for this study is available for download from the Short Read Archive database at: http://www.ncbi.nlm.nih.gov/Traces/sra/sra.cgi?study=SRP000703. For data usage terms and conditions, please refer to http://www.genome.gov/27528022 and http://www.genome.gov/Pages/Research/ENCODE/ENCODEDataReleasePolicyFinal2008.pdf

2008-09-16 | GSE12782 | GEO

A role for ZNF598 in post-transcriptional gene regulation

Project description:Transcriptomic changes in U2OS cells upon depletion of the RNA-binding protein ZNF598 were analyzed in non-treated and IL-1 beta treated cells in comparison to control U2OS cells

2019-03-26 | GSE116126 | GEO

Poly(A) tail length change of miRNA targets in HeLa cells

Project description:MicroRNA induces deadenylation of its targets according to the current model in the scientific community, but this model is based on the studies of a few individual genes. We tested the model by examining the global effect of miRNA on poly(A) tail of the targets. Synthetic miR-1 mimic was transfected into HeLa cells, and the poly(A) length was measured by TAIL-seq. Deadenylation of miR-1 targets was evident as early as 3 hours post-transfection without a significant change in mRNA level. After 6 or 9 hours, target mRNA level was substantially downregulated. Therefore, although there are some exceptions, our result confirms that, in general, miRNA indeed induces deadenylation. Furthermore, our kinetic global analysis confirms that deadenylation precedes mRNA decay. Four culture dishes of HeLa cells were treated with miR-1 all together, then collected and prepared for sequencing after different time of incubation (0, 3, 6, and 9 hours post-transfection)

2014-02-28 | E-GEOD-54114 | biostudies-arrayexpress

Poly(A) tail length change of miRNA targets in HeLa cells

2014-02-28 | GSE54114 | GEO