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Expression data from primary murine CD8+ T cells incubated in AML cell or dendritic cell conditioned medium

ABSTRACT: Expression data from primary murine CD8+ T cells incubated in AML cell or dendritic cell conditioned medium

PROVIDER: PRJNA561354 | ENA |

REPOSITORIES: ENA

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Expression data from primary murine CD8+ T cells incubated in AML cell or dendritic cell conditioned medium

Project description:During activation T cells need to undergo metabolic reprogramming for proper effector function. Disturbances in metabolic pathways lead to impaired T cell function. Active metabolic evasion of cancer cells lead to less immunosurveillance and uncontrolled tumor growth. We used microarrays to investigate the expression changes in T cells challenged with AML supernatants shedding light on the underlying mechanisms of metabolic evasion in leukemia.

2023-08-21 | GSE136132 | GEO

Analysis by Whole Transcriptome Sequencing of the Effects of LLC1 conditioned medium, LLC1 conditioned plus Calcitriol, non-conditioned medium, and non-conditioned medium plus Calcitriol on mRNA Expression in Primary Human Skeletal Muscle Cells

Project description:Primary human skeletal muscle cells (Lonza) were treated with LLC1 conditioned medium, LLC1 conditioned medium plus Calcitriol, LLC1 non-conditioned medium or LLC1 non-conditioned medium plus Calcitriol for a period of 24 hours prior to isolation of RNA.

2018-02-07 | GSE103549 | GEO

RNA sequencing of adult mouse ventricular cardiomyocytes incubated in normal growth medium or medium conditioned by CCR2+ cardiac macrophages

Project description:RNA-sequencing of primary cultured adult mouse cardiomyocytes under control conditions or cultured for 24h with medium conditioned by CCR2+ macrophages isolated from pressure overloaded mouse hearts

2023-08-02 | GSE196798 | GEO

RNA sequencing of adult mouse ventricular cardiomyocytes incubated in normal growth medium or medium conditioned by CCR2+ cardiac macrophages

Project description:RNA sequencing of adult mouse ventricular cardiomyocytes incubated in normal growth medium or medium conditioned by CCR2+ cardiac macrophages

| PRJNA807329 | ENA

RNA from mouse lung conditioned medium

Project description:RNA from mouse lung conditioned medium

| PRJNA675882 | ENA

RNA-seq data of human T cells treated with decidual cell conditioned medium

Project description:RNA-seq data of Naïve T cells treated with decidual cell conditioned medium. Naïve T cells were differentiated into Th17 cells by IL6, TGFB1, and IL23 stimulation, in the presence of either unconditioned (control) or conditioned medium from uterine decidual stromal cells

2020-07-01 | GSE120380 | GEO

Protein Amount in Conditioned Medium of MenSCs

Project description:Protein Amount in Conditioned Medium of MenSCs

| PRJNA950089 | ENA

RNA from mouse lung conditioned medium

Project description:RNA fragments were isolated from mouse lung conditioned medium and analyzed by a microarray This analysis surveys RNAs, probably complexed with RNA-binding protein, secreted in the culture media

2021-04-11 | GSE161219 | GEO

Effect of tumor conditioned medium of human mesenchymal stem cell (MSCs)

Project description:We have employed whole genome microarray to identify changes in gene expression in human MSCs exposed to tumor conditioned medium

2013-09-11 | GSE50722 | GEO

Gene expression in macrophages polarized with conditioned medium from wild-type or Snail1-depleted cancer-activated fibroblasts

Project description:Snail1 is a transcriptional factor required for activation of cancer-associated fibroblasts (CAF). In a murine model of mammary gland cancer, mice with Snai1 gene deletion presented a greater survival and differences in macrophage differentiation with fewer M2 macrophages. Snail1 was not expressed in macrophages and in vitro polarization of monocytes towards M1 or M2 phenotypes was not altered by Snai1 gene depletion. In contrast, when macrophages were incubated with Snail1-expressing CAF or with conditioned medium derived from these cells, they exhibited a lower cytotoxic capability than when incubated with Snail1 KO (inactive) CAFs. We compared gene expression of macrophages polarized by CAF WT versus CAF KO-conditioned medium with that promoter by IFN gamma and IL4, classical M1 and M2 inducers, respectively. We observed that, compared to inactive fibroblasts, active CAF specifically upregulated the expression of some M2 genes as Arg1 and also of genes normally reduced in M1 polarization, such as Arg2, although the gene pattern differed from that stimulated by IL4. A complete list of these genes is presented here.

2023-08-09 | GSE206404 | GEO

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