Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

ABSTRACT: Impact of fiber-based enteral nutrition on the gut microbiome of ICU patients receiving broad-spectrum antibiotics: a randomized pilot trial

PROVIDER: PRJNA603980 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR10994524_1.fastq.gz	Fastqsanger.gz
	SRR10994524_2.fastq.gz	Fastqsanger.gz
	SRR10994525_1.fastq.gz	Fastqsanger.gz
	SRR10994525_2.fastq.gz	Fastqsanger.gz
	SRR10994526_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 152

Similar Datasets

Neonatal antibotic prophylaxis modulates intestinal immunity and prevents necrotizing enterocolitis in preterm neonates

Project description:Caesarean-delivered preterm pigs were fed 3 d of parenteral nutrition followed by 2 d of enteral formula feeding. Antibiotics (n=11) or control saline (n=13) were given twice daily from birth to tissue collection at d 5. NEC-lesions and intestinal structure, function, microbiology and immunity markers were recorded. We used Affymetrix microarrays to investigate gene expression in intestinal tissues of preterm piglets treated with antibiotics or control saline. Twenty-four preterm piglets were delivered by caesarean section on day 105 of gestation from two healthy sows. All piglets were initially provided with parenteral nutrition via a vascular catheter, combined with small amounts of minimal enteral nutrition. On day three, all parenteral nutrition was stopped and total enteral nutrition was given through an oro-gastric feeding tube. Piglets were allocated into controls ( n=13) and an intervention group receiving oral and systemic broad-spectrum antibiotics ( n=11). To assure high systemic and intra luminal MIC values antibiotics were given both orally and intramuscularly. All antibiotics were given directly after feeding with an oral bolus and control pigs were given corresponding amounts of saline. On day five, all piglets were euthanized, and small intestinal tissue collected.

2013-08-21 | E-GEOD-48125 | biostudies-arrayexpress

Neonatal antibotic prophylaxis modulates intestinal immunity and prevents necrotizing enterocolitis in preterm neonates

2013-08-21 | GSE48125 | GEO

Project description:Broad-spectrum antibiotics disrupt homeostatic efferocytosis

| PRJNA1128534 | ENA

Broad-spectrum antibiotics disrupt homeostatic efferocytosis [scRNA-seq]

Project description:Broad-spectrum antibiotics disrupt homeostatic efferocytosis [scRNA-seq]

| PRJNA1127434 | ENA

A microbiome-dependent gut–brain pathway regulates motivation for exercise

Project description:Single nucleus RNA sequencing of mouse striatum at steady state and after exercise in mice treated and untreated with broad spectrum antibiotics.

2022-09-19 | GSE210906 | GEO

Broad-spectrum antibiotics disrupt homeostatic efferocytosis [bulk RNA-seq]

Project description:Broad-spectrum antibiotics disrupt homeostatic efferocytosis [bulk RNA-seq]

| PRJNA1127440 | ENA

The effect of nutrient deprivation on early life small intestine mucosal microbiome and host proteome

Project description:Nutrition has a vital role in shaping the intestinal microbiome. The impact of nutrients and the consequences of enteral deprivation on the small intestinal mucosal microbiota, specifically in early life, has not been well described. Our aim was to study the impact of enteral deprivation on the small intestine mucosal microbiome and to search for factors that shape this interaction in early life. Host seem to be the most dominant factor in the structure of the early life mucosal microbial small intestine community. Under conditions of nutrient deprivation, there are specific changes in host proteomics. Further research is needed to better define and understand this host-microbe-nutrition interaction in the small intestine.

2024-07-16 | PXD044961 | Pride

Hirschprung Enterocolitis SCFA

Project description:Children with Hirschsprung disease (HD) who have a history of enterocolitis (HAEC) have a shift in colonic microbiota, many of which are necessary for short chain fatty acid (SCFA) production. As SCFAs play a critical role in colonic mucosal preservation, we hypothesized that fecal SCFA composition is altered in children with HAEC. Patients between age of 6 weeks and 16 years of age who were undergoing small bowel resection were selected, including those who were either receiving enteral nutrition preoperatively (control group), or those who were without enteral nutrition and receiving total parenteral nutrition (TPN group). At the time of operation, 100-500µl of effluent from the small bowel lumen was aspirated during the small bowel resection. The samples were immediately frozen in liquid nitrogen and stored at -80oC. Research is published: http://www.sciencedirect.com/science/article/pii/S0022346815006211

2015-06-08 | ST000189 | MetabolomicsWorkbench

Project description:Gut microbiome difference between prebiotic enriched and fiber-free exclusive enteral nutrition in mice

| PRJNA731528 | ENA

Project description:Effects of broad-spectrum antibiotics on graft-versus-host disease

| PRJEB12959 | ENA