Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

ABSTRACT: Chlordecone biotransformation study

PROVIDER: PRJNA608607 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR11178758_1.fastq.gz	Fastqsanger.gz
	SRR11178758_2.fastq.gz	Fastqsanger.gz
	SRR11178759_1.fastq.gz	Fastqsanger.gz
	SRR11178759_2.fastq.gz	Fastqsanger.gz
	SRR11178760_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 27

Similar Datasets

Prostate H3K4me3 ChIP-seq

Project description:Exposure to pesticide chlordecone is associated with high risk of prostate cancer.We hypothesised that changes in histone H3K4me3 could be involved in pathological processes in prostate induced by chlordecone. We exposed mice to chlordecone during embryonic development (E6.5-E15.5) and we analysed F1 progeny male epigenetic H3K4me3 marks in prostate tissue, as well as H3K4me3 in the prostate of F3 progeny to reveal the transgenerational effects resulting from the ancestral exposure to CD. We performed ChIP using H3K4me3 commercial antibody (Merck Millipore, 07-473) and pooled prostate tissues from 4 mice. DNA-protein complex was immunoprecipitated, eluted and DNA purified.

2021-04-01 | GSE135199 | GEO

Histone mark modifications in murine ovary after gestational exposure to chlordecone

Project description:We hypothesized that gestational exposure to chlordecone can lead to alteration of murine ovary's epigenetic landscape. To test our hypothesis, we exposed mice to chlordecone during embryonic development and we analyzed F1 female progeny epigenetic mark H3K4me3 in ovaries. We performed ChIP using anti-H3K4me3 commercial antibody (Merck Millipore, 07-473). DNA-protein complexes were immunoprecipitated, eluted and then DNA were purified.

2019-05-21 | GSE129897 | GEO

fermentation metagenome

Project description:the study of microalgal biotransformation

| PRJNA530352 | ENA

Transgenerational effect of Chlordecone [RNA-seq]

Project description:RNA seq project designed to understand the role of pesticide on transription of mRNA in the testis. We treated adult female mice with chlordecone with doses 0 (control), 100 Xg/kg/day and 1 mg/kg/day during gestation period E6- E15. Male born from Chlordecone- treated mice were crossed for a three generations. The testes from F3 generations were taken for mRNA extraction. For mRNA extraction we used columb. Three biological replicates used for each condition . We hypothesize that chlordecone cause changes in mRNA due to transgenerational effect of pesticides (Skinner et al, Science 2005). The changes in expression of certain genes can help us understand the effect of pesticides on many tissues. Number of sample :9 samples. We require Paired End sequencing and number of reads equal or more than 25M tags, strand specific sequencing

2018-07-10 | GSE86438 | GEO

Transgenerational effect of Chlordecone

Project description:Transgenerational effect of Chlordecone

| PRJNA341868 | ENA

High-throughput transcriptome sequencing analysis provides insights into preliminary biotransformation mechanism of Rhodopseudomonas palustris treated with alpha-rhamnetin-3-rhamnose

Project description:In this paper, we present the first comparative transcriptome profiles with ARR treated and control of R. palustris. Moreover, putative two ARR biotransformation mechanisms in R. palustris were first given. All of these provided a valuable genomic resource for further studying molecular mechanism of biotransformation and genetic modification of R. palustris.

2018-06-04 | GSE69576 | GEO

Biochemical characterization, biosynthesis mechanism, and functional evaluation of selenium-enriched Aspergillus oryzae A02

Project description:The synthesis mechanisms and function evaluation of selenium(Se)-enriched microorganism remain relatively unexplored. We here report the Se biotransformation by A. oryzae A02. Comparative RNA-Seq analysis revealed the upregulation of functional genes implicated in selenium transformation, activating multiple potential pathways for selenium reduction. The assimilatory and dissimilatory reductions of Se oxyanions engaged numerous parallel and interconnected pathways, manifesting a harmonious equilibrium in overall Se biotransformation in A. oryzae A02.

2024-07-07 | GSE270867 | GEO

Project description:Biotransformation of Phosphogypsum

| PRJNA650275 | ENA

Mus musculus

Project description:Transgenerational effect of Chlordecone [ChIP-seq]

| PRJNA341897 | ENA

Mus musculus

Project description:Transgenerational effect of Chlordecone [RNA-seq]

| PRJNA341898 | ENA