Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Next generation sequencing identifies differentially expressed genes between breast cancer with diabetes and breast cancer without diabetes

ABSTRACT: Next generation sequencing identifies differentially expressed genes between breast cancer with diabetes and breast cancer without diabetes

PROVIDER: PRJNA632870 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR11790419_1.fastq.gz	Fastqsanger.gz
	SRR11790419_2.fastq.gz	Fastqsanger.gz
	SRR11790420_1.fastq.gz	Fastqsanger.gz
	SRR11790420_2.fastq.gz	Fastqsanger.gz
	SRR11790421_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 26

Similar Datasets

Next generation sequencing identifies differentially expressed genes between breast cancer with diabetes and breast cancer without diabetes

Project description:We report the application of RNA-sequencing for high-throughput profiling of transcriptomes in tumor tissues from patients with breast cancer and diabetes, and in tumor tissues from breast cancer patients without diabetes.

2020-05-16 | GSE150586 | GEO

Identification of lncRNAs Differentially Expressed in Basal-like Breast Cancer

Project description:Identification of lncRNAs Differentially Expressed in Basal-like Breast Cancer

| PRJNA488557 | ENA

Differentially Expressed Genes Regulating the Progression of Ductal Carcinoma In Situ to Invasive Breast Cancer

Project description:This SuperSeries is composed of the following subset Series: GSE41194: Differentially Expressed Genes Regulating the Progression of Ductal Carcinoma In Situ to Invasive Breast Cancer (Group 1) GSE41196: Differentially Expressed Genes Regulating the Progression of Ductal Carcinoma In Situ to Invasive Breast Cancer (Group 2) GSE41197: Differentially Expressed Genes Regulating the Progression of Ductal Carcinoma In Situ to Invasive Breast Cancer (Group 3) GSE41198: Differentially Expressed Genes Regulating the Progression of Ductal Carcinoma In Situ to Invasive Breast Cancer (Group 4 stroma) GSE41227: Differentially Expressed Genes Regulating the Progression of Ductal Carcinoma In Situ to Invasive Breast Cancer (Group 4 Epithelial) Refer to individual Series

2012-09-29 | E-GEOD-41228 | biostudies-arrayexpress

Diabetes-associated breast cancer has a distinct transcriptome and metabolome and shows DNA repair deficiency [Breast Tumors]

Project description:Diabetes commonly affects cancer patients. As a comorbidity, it may modify tumor biology and therapy response. Yet, we still lack an understanding of the diabetes-induced molecular changes in human breast tumors and their implication for therapy. The goal of this study was aimed to identify diabetes induced phenotypes and molecular signatures in breast cancer. Here, we investigated the effect of diabetes on breast cancer biology using a three-pronged approach that included analysis of orthotopic human tumor xenografts, patient tumors, and breast cancer cells exposed to diabetes and hyperglycemia. Diabetes and hyperglycemia induced a mesenchymal and stem cell-like phenotypes. Further Diabetes and hyperglycemia also associated with oxidative stress and both gene expression and mutational signatures of DNA repair deficiency. Breast cancer cells cultured under hyperglycemia acquired increased DNA damage and sensitivity to DNA damage response inhibitors. Based on these observations, diabetes-associated breast tumors may show an increased drug response to DNA repair pathway inhibitors that are cancer therapeutics.

2023-11-07 | GSE202922 | GEO

Diabetes-associated breast cancer has a distinct transcriptome and metabolome and shows DNA repair deficiency [Xenografts]

2023-11-07 | GSE202599 | GEO

Identified differentially expressed lncRNAs in Type 1 Diabetes Patients

Project description:Identified differentially expressed lncRNAs in Type 1 Diabetes Patients

| PRJNA534518 | ENA

Identified differentially expressed lncRNAs in type 2 diabetes patients

Project description:Identified differentially expressed lncRNAs in type 2 diabetes patients

| PRJNA555791 | ENA

Diabetes-associated breast cancer has a distinct transcriptome and metabolome and shows DNA repair deficiency [RNAseq-Hs578T]

2023-11-07 | GSE236419 | GEO

Diabetes-associated breast cancer has a distinct transcriptome and metabolome and shows DNA repair deficiency [MDAMB157 cell lines]

2023-11-07 | GSE202598 | GEO

Identified differentially expressed lncRNAs in type 2 diabetes patients

Project description:Long noncoding RNAs (lncRNAs) is already evidently involved in a variety of biological functions and pathophysiological mechanisms underlying the diabetes. However, the role of lncRNAs in the type 2 diabetes (T2D) has not been explored clearly yet. The aim of this study was to determine the circulating lncRNA profile and confirmed the differentially expressed lncRNA between T2D patients.

2020-06-30 | GSE134594 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data