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RNA-seq analysis of Molm-13 cell with GADD45g overexpressed

ABSTRACT: RNA-seq analysis of Molm-13 cell with GADD45g overexpressed

PROVIDER: PRJNA641010 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR12066443.fastq.gz	Fastqsanger.gz
	SRR12066444.fastq.gz	Fastqsanger.gz
	SRR12066445.fastq.gz	Fastqsanger.gz
	SRR12066446.fastq.gz	Fastqsanger.gz

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RNA-seq analysis of Molm-13 cell with GADD45g overexpressed

Project description:The growth arrest and DNA-damage induced 45 gamma (GADD45g) is rapidly induced by various physiological and environmental stresses associated with growth arrest. GADD45g has been observed implicated in cell survival, apoptosis, senescence, cell cycle regulation and DNA repair in a variety of human solid tumor types, acting as either tumor promoter or tumor suppressor. To date, the role of GADD45g in hematopoietic malignancies remains completely unknown. Here, we transduced Molm-13 cells with lentiviral vectors expressing doxycycline-inducible GADD45g. Molm-13 cells with dox administration or not were collected for RNA-seq.

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