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Transcriptome profile of INS-1E Ctrl and hTFEB OE cells

ABSTRACT: Transcriptome profile of INS-1E Ctrl and hTFEB OE cells

PROVIDER: PRJNA648985 | ENA |

REPOSITORIES: ENA

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Transcriptome profile of INS-1E Ctrl and DKO cells

Project description:Transcriptome profile of INS-1E Ctrl and DKO cells

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Transcriptome profile of INS-1E Ctrl and hTFEB OE cells

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Interactome of Ca2+-bound secretagogin in INS-1E cells

Project description:By using His6-tagged recombinant human secretagogin in the presence of Ca2+ (100 µM), we precipitated putative interacting partners from INS-1E cells and identified their amino acid sequences by mass spectrometry. We detected canonical interacting proteins participating in vesicle-mediated transport, exocytosis and cytoskeletal organization. Besides, we captured proteins controlling protein folding and (de-)ubiquitination. Our data support that secretagogin modulates protein folding and degradation through protein-protein interactions and interacts with USP9X in β cells to control cell survival.

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Expression data from rat INS-1E cells

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MiRNA profiling in Rattus norvegicus pancreatic cells: INS-1E cells during infection with Coxsackie B4 virus

Project description:This study aims at elucidating how Coxsackie B virus infection perturbs the host's miRNA regulatory pathways that may lead to different pathological events using the miRNA microarray approach. The rat pancreatic cell line - INS-1E, was infected with various preparations of Coxsackie B4 viruses was analysed for miRNA expression profiles subsequently. The miRNA expression profiles were measured at 48, and 72 hours post infection, respectively.

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Time course treatment with Palmitate and thapsigargin of insulinoma INS-1E cells

Project description:Time course treatment with 0.4 mM Palmitate and 200 nM thapsigargin of insulinoma INS-1E cells. Timepoints; 0, 4, 16 and 24h in biological duplicates within an iTRAQ 8 set for palmitate and thapsigargin, respectively.

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Transcription profiling of rat insulinoma-beta (INS-1E) cells exposed to the cytokines IL-1-beta and IFN-gamma for six different lengths of time and with or without the inducible NO synthase blocker NMA

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Project description:RNASeq of Ins-1E cells with internalised apoA-I (apoA-I positive) and Ins-1E cells without internalised apoA-I (apoA-I negative) from 3 independent experiments.

| PRJEB50345 | ENA

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