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Next generation sequencing of migratory Innate lymphoid cells, T cells and dendritic cells in mesenteric lymph

ABSTRACT: next generation sequencing of migratory Innate lymphoid cells, T cells and dendritic cells in mesenteric lymph

PROVIDER: PRJNA672118 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR12900929_1.fastq.gz	Fastqsanger.gz
	SRR12900929_2.fastq.gz	Fastqsanger.gz
	SRR12900930_1.fastq.gz	Fastqsanger.gz
	SRR12900930_2.fastq.gz	Fastqsanger.gz
	SRR12900931_1.fastq.gz	Fastqsanger.gz

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Expression data from pig mesenteric lymph nodes

Project description:The mesenteric lymph nodes represent the immune response to eggs in schistosome infections,and the analysis of gene expression profiles of the mesenteric lymph nodes from the Vac-Cha (vaccinated with UV attenuated cercariae and challenged with normal cercariae)and Inf-Con (infected with normal cercariae) groups. We used microarrays to detail the global programme of gene expression and identified distinct classes of up-regulated and down-regulated genes. The mesenteric lymph nodes surrounding the cecum from the Vac-Cha and Inf-Con groups were collected at week 8 post challenge and used to analyze the gene profile with Affymetrix microarrays. We sought to obtain the different genes expression profiles between the Vac-Cha group and Inf-Con group.The Vac-Cha group is three pigs vaccinated with UV attenuated Schistosoma japonicum cercariae and challenged with normal Schistosoma japonicum cercariae, and the Inf-Con group is three pigs infected with normal cercariae. Samples pooled per group. A list of differentially-regulated genes can be found in the supplementary file below.

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