Project description:Microarrays data of wild-type and mutant worm(RB1884) were used to determin which genes in the nematode were expressed depednet on mnp-1 To identify the genes that are key factors involved in MNP-1 mediated protection against Cry5Ba
Project description:The hlh-30 gene encodes a C. elegans basic-helix-loop-helix (bHLH) transcription factor; We compared RNA from wild type worms and worms mutant for the hlh-30 gene to identify putative target genes of the HLH-30 transcription factor.
Project description:Purpose: To identify the mechanism underlying reduced vitellogenin accumulation regulates the reproductive span, we used RNA-Seq analysis to study the transcriptional profiles Wild Type worms and vit-5 RNAi worms.
Project description:Analysis of gene expression in worms exposed to PA14 for 4 hours. Worms used were wild-type or fshr-1(ok778) mutants. Comparisons allowed determination of fshr-1-dependent gene expression.
Project description:PKA/KIN-1 pathway is required for innate immunity in C. elegans, however, the downstream signaling is largely unclear. To gain further insight into mechanism underlying the promoted immunity of PKA/KIN-1 pathway, we performed genome microarrays of wild-type and kin-1(ok338) worms infection by Salmonella entericSL1344, compared with the controls wild-type fed E.coli OP50
Project description:The SPT-2 histone chaperone is involved in the maintenance of chromatin structure during transcription. Here, we performed mRNA-seq to compare gene expression profiles of spt-2 mutant worms. We compare two full spt-2 gene knock-out worm strains (KO-A and KO-B), or a strain expressing an spt-2 allele with reduced binding to histones (M627A), to wild type N2 worms.