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Ribosome profiling experiments of LRRK2 mouse models

ABSTRACT: Ribosome profiling experiments of LRRK2 mouse models

PROVIDER: PRJNA705181 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR13794627.fastq.gz	Fastqsanger.gz
	SRR13794628.fastq.gz	Fastqsanger.gz
	SRR13794629.fastq.gz	Fastqsanger.gz
	SRR13794630.fastq.gz	Fastqsanger.gz
	SRR13794631.fastq.gz	Fastqsanger.gz

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Ribosome profiling experiments of LRRK2 mouse models

Project description:G2019S mutaion of LRRK2 is known to increase mRNA translation. We perform ribosome profiling to study defective translation in mammalian LRRK2 models. We used G2019S LRRK2 transgenic mice, G2019S/D1994A LRRK2 transgenic mice, LRRK2 knockout mice.

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Effects of cycloheximide (CHX) on ribosome profiling experiments in Schizosaccharomyces pombe

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Humans and other commonly used model organisms are resistant to cycloheximide-mediated biases in ribosome profiling experiments

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