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Changes in miRNA expression profile upon treatment with plumbagin or menadione in SW-620 colorectal cancer cells

ABSTRACT: Changes in miRNA expression profile upon treatment with plumbagin or menadione in SW-620 colorectal cancer cells

PROVIDER: PRJNA809700 | ENA |

REPOSITORIES: ENA

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Changes in miRNA expression profile upon treatment with plumbagin or menadione in SW-620 colorectal cancer cells

Project description:To elucidate the mode of actions of Plumbagin and Menadione, miRNA-profilling was performed after treating cells with vehicle (DMSO), Plumbagin (10uM), and Menadione (10uM) for 24 hours. Threel replicates for control and Menadione and two replicates for Plumbagin were subjected to miRNA-microarray.

2023-03-01 | GSE197300 | GEO

Expression data from plumbagin-treated B16F10

Project description:Gene expression profiling reveals a potential role of plumbagin on the induction of B16F10 metastasis cells were treated with 0 and 2 µM plumbagin for 24 h ; Microarray gene expression profiling was conducted.

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Mycobacterium tuberulosis H37Rv strains: Control vs. Plumbagin

2010-09-20 | GSE24045 | GEO

Mycobacterium tuberulosis H37Rv strains: Control vs. Plumbagin

Project description:Transcriptional profiling of Mycobacterium tuberculosis H37Rv strains comparing control DMSO treated strains with Plumbagin treated strains. Goal was to determine the effects of Plumbagin against Mycobacterium tuberculosis H37Rv strains. Two-condition experiment,control DMSO vs. Plumbagin. Biological replicates: 2 control replicates, 2 Plumbagin replicates. The file showing raw and normalized data (~4645 rows) extracted from Agilent Feature Extraction Software is linked below. Samples details are described in PDF file linked below (NOTE: The samples 'Plumbagin' and 'chelerythrine' represent the submissions to GEO).

2010-09-20 | E-GEOD-24045 | biostudies-arrayexpress

Differential gene expression induced by anti-cancer agent plumbagin is mediated by androgen receptor in prostate cancer cells

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2017-09-28 | GSE104305 | GEO

Transcriptome profiling of E. coli under different naphthoquinone treatments

Project description:E. coli MG1655 was grown in the presence of either PL (Plumbagin)/JU (Juglone)/ME (Menadione) (50 micro molar) and DMSO (0.75%)as control, and subjected to microarray analysis. The aim of the work was to understand the structure-function relationship between plumbagin and its analogues.

2013-08-14 | E-MEXP-3765 | biostudies-arrayexpress

Expression data from MCF-7 breast cancer cells treated with Plumbagin (PL) and its derivative Acetyl Plumbagin (AP)

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Rhodospirillum centenum SW strain:SW

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Gene expression changes induced by overexpression of PJA2 in SW-480 cells

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Transcript Level Expression Profiling: anticancer pathways of Smilax Glabra rhizome extract (SW)

Project description:Find the possible signaling pathways which contribute to the cell growth inhibition effect of SW-treated AGS cells Global gene expression profiling is an ideal technique to obtain useful clues for exploration of the anticancer mechanism of SW. Through comparing microarray results between solvent- and SW-treated cells, differentially expressed genes were obtained (>1.5 fold). The microarray results were validated using real-time RT-PCR. We used the KEGG database, STRING database and GO database for further ananlysis, and therefore got the possible signaling pathways underlying the anticancer effect of SW.

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