Project description:Mouse myofibroblastic EMS404 cells were transfected using a siRNA directed against BNC2 (siBNC2) or a control siRNA (siCTRL) and RNA were processed for microarray analyses.
Project description:Human myofibroblastic LX2 cells were transfected using a siRNA directed against BNC2 (siBNC2) or a control siRNA (siCTRL) and RNA were processed for microarray analyses.
Project description:The Ayu21-18 mouse line (B6;CBA-Bnc2Gt(pU21)18Imeg/Orl; Infrafrontier EM-05043) was used to generate mice with heterozygous inactivation of Bnc2,which were compared to their wild-type (WT) littermates. Mice were fed a pro-fibrogenic NASH diet for 7.5 weeks and livers were used used to prepare RNA.