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RNA-seq analysis of Alyref and Gabpb1 knockout embryos

ABSTRACT: RNA-seq analysis of Alyref and Gabpb1 knockout embryos

PROVIDER: PRJNA821878 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR18560223_1.fastq.gz	Fastqsanger.gz
	SRR18560223_2.fastq.gz	Fastqsanger.gz
	SRR18560224_1.fastq.gz	Fastqsanger.gz
	SRR18560224_2.fastq.gz	Fastqsanger.gz
	SRR18560225_1.fastq.gz	Fastqsanger.gz

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RNA-seq analysis of Alyref and Gabpb1 knockout embryos

Project description:We have identified Alyref and Gabpb1 as developmentally important genes by siRNA screening. Gene knockout (KO) of Alyref and Gabpb1 by the CRISPR/Cas9 system resulted in early developmental arrest in mice. To gain mechanistic insight into the developmental role of Alyref and Gabpb1, we performed RNA sequencing (RNA-seq) analysis of the KO embryos.

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ALYREF is shared by polyadenylated and nonpolyadenylated mRNA processing and export pathways [iCLIP-seq]

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