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Homo sapiens isolate:Lymph node | cultivar:H1299

ABSTRACT: BTApep-TAT suppressed the proliferation of H1299 lung cancer

PROVIDER: PRJNA832514 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR19173553.fastq.gz	Fastqsanger.gz
	SRR19173554.fastq.gz	Fastqsanger.gz
	SRR19173555.fastq.gz	Fastqsanger.gz
	SRR19173556.fastq.gz	Fastqsanger.gz
	SRR19173557.fastq.gz	Fastqsanger.gz

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Knockdown LRRK1-CAPT in NCI-H1299 lung cancer cell line

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Proteome of silenced minichromosome maintenance protein 2 with siRNA on non-small cell lung cancer H1299 cells

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Expression data from NCI-H1299 and NCI-H1299/CDDP cells

Project description:Non-small cell lung cancer (NSCLC) patients are prone to drug resistance during chemotherapy. Therefore, in order to compare the changes in the gene expression profiles of NSCLC cells before and after drug resistance, we constructed cisplatin-resistant cells (NCI-H1299/CDDP), and compared the gene expression profiles with those of the parental NCI-H1299 cells. We used microarrays to study in detail the global gene expression changes before and after drug resistance in NSCLC cells and identified genes that were up- or down-regulated during this process.

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