Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

The transcriptomic profile of rabiës virus (RABV) exposed human monocyte-derived macrophages.

ABSTRACT: The transcriptomic profile of rabiës virus (RABV) exposed human monocyte-derived macrophages.

PROVIDER: PRJNA848773 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR19636019.fastq.gz	Fastqsanger.gz
	SRR19636020.fastq.gz	Fastqsanger.gz
	SRR19636021.fastq.gz	Fastqsanger.gz
	SRR19636022.fastq.gz	Fastqsanger.gz
	SRR19636023.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 15

Similar Datasets

The transcriptomic profile of rabiës virus (RABV) exposed human monocyte-derived macrophages.

Project description:Macrophages are amongst the first immune cells that encounter rabies virus (RABV) at injured sites, but insights into if and how RABV affects macrophage activation are scarce. We undertook this study to characterize the transcriptional profile of human monocyte-derived macrophages that were exposed to RABV in vitro, to examine the antiviral response and potential RABV-induced immunosuppression mechanisms in these cells.

2022-06-16 | GSE205990 | GEO

Transcriptome profile of the host antiviral response to Chikungunya virus infection in human monocyte-derived macrophages (MDMs)

Project description:Chikungunya virus (CHIKV) infection is characterized by alterations in gene expression profile on host cells that consequently lead to an immune response. Here, we used RNA sequencing to analyze the mRNA expression profile in human monocyte-derived macrophages (MDMs) infected with a Colombian clinical isolate of CHIKV at 6 and 24 hpi. analyze the mRNA expression profile in the human monocyte-derived macrophages infected at 6 and 24 hrs with a Colombian clinical isolate of Chikungunya virus.

2022-01-19 | GSE193977 | GEO

RNA-seq of Human monocyte derived macrophages exposed to arachidonic acid, IL6 or both

Project description:Monocyte derived macrophages were exposed to arachidonic acid, IL6 or both.

2021-12-31 | E-MTAB-10868 | biostudies-arrayexpress

Monocyte-derived Macrophages

Project description:Monocyte-derived Macrophages

| PRJNA948022 | ENA

RNA-seq of monocyte derived macrophages exposed to arachidonic acid, interferon beta, or interferon gamma

Project description:Monocyte derived macrophages were exposed to arachidonic acid, interferon beta, or interferon gamma

2021-12-31 | E-MTAB-10867 | biostudies-arrayexpress

Transcriptional profile regulated by 1,25-dihydroxyvitamin D (Calcitriol) in primary Human Monocyte-Derived Macrophages infected by zika virus

Project description:ZIKA virus (ZIKV) infection is characterized by alterations in gene expression profile on host cells that consequently lead to an immune response. Here, we used RNA sequencing to analyze the mRNA and miRNA expression profile in human monocyte-derived macrophages (MDMs) differenitated in presenece of 1,25-dihydroxyvitamin D (Calcitriol) and infected with a Zika virus strain COL345Si-Asian at MOI of 5 and analized 24 hpi.

2023-03-15 | GSE209698 | GEO

Analyses of Methamphetamine-Exposed and HIV- infected Human Monocyte-Derived Macrophages (hMDM)

Project description:Human monocyte-derived macrophages (hMDM) were differentiated in the presence and absence of methamphetamine. Post differentiation, hMDMs were infected with human immunodeficiency virus (HIVADA). To investigate the effects of Meth exposure on infected macrophages day 5 post HIVADA infection, RNA was isolated from HIVADA hMDMs and sequenced using Next Generation Sequencing performed on the Illumina NextSeq550.

2021-09-28 | GSE160323 | GEO

Transcriptome profile of human dermal macrophages and monocyte-derived macrophages

Project description:DC, monocyte and macrophage networks are evolutionarily conserved but the distinct subsets have been difficult to distinguish due to shared overlapping phenotypic markers between the cells. Using transcriptome microarray profiling of human and mouse mononuclear phagocyte subsets, we have distinguished human dermal DCs from monocyte-derived cells and macrophages. Gene Expression from total RNA from human dermal macrophages, epidermal LCs and CD14+ cells subsets purified by FACS

2014-10-15 | E-GEOD-60317 | biostudies-arrayexpress

RNA-seq of human monocyte derived macrophages exposed to different atherogenic compounds

Project description:The accumulation of lipid-laden macrophages (foam cells) in the arterial wall is a crucial early step in atherosclerotic plaque development. Modified low-density lipoprotein (LDL) is the primary cholesterol source for foam cells, taken up in an unregulated manner through scavenger receptors. This type of cells exhibit reduced migratory capacity while producing elevated levels of pro-inflammatory cytokines, thereby promoting inflammation and plaque progression. Still our understanding of the transcriptomic changes during macrophage-to-foam cell conversion remains limited. In this experiment, we aimed to identify genes responsible for the accumulation of cholesterol in human monocyte-derived macrophages exposed to modified and native LDL. The monocyte samples collected from healthy individuals were purified and exposed to modified and native LDLs obtained from plasm of atherosclerotic patients. RNA extracted after 24h of incubation was sequenced with polyA selection. The resulting data was normalised with limma and undergone DEG analysis followed by upstream analysis workflow with TRANSPATH and TRANSFAC databases to discover master regulator molecules.

2023-08-14 | E-MTAB-13261 | biostudies-arrayexpress

MHC I-restricted immunopeptidomics analysis of human monocyte-derived macrophages exposed to biological nanoparticles bearing influenza hemagglutinin

Project description:In this study, primary human monocyte-derived macrophages were exposed to plant-derived virus-like particles (VLPs) bearing influenza A hemagglutinin (HA) or soluble influenza HA, as control. Immunopurified MHC class I-associated peptides were analysed by nano-flow high pressure liquid chromatography coupled to high-resolution dopant-assisted electrospray ionisation mass spectrometry. A total of 109 host-derived MHC I peptides were identified in the VLP-treated samples, two of which were also detected in controls. The peptides unique to VLP treatment were, on average, ~13 amino acid residues long, more basic and hydrophilic, and were mainly processed via proteolysis by matrix metalloproteinases and cathepsins. The proteins associated with these peptides were primarily involved in cellular, metabolic and regulatory processes and activated several pathways including inflammation stimulation and attenuation, response to stimuli, innate and adaptive immunity, clathrin-mediated endocytosis, protein synthesis and endo-lysosomal degradation. This study is the first report to describe the response of a primary human antigen-presenting cell to nanoparticulate vs. soluble antigen exposure from an immunopeptidomics point of view.

2022-02-24 | PXD010741 | Pride

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data